Havent checked into neem safer soap? I imagine its just neem with a organic biodegradable soap? If so yes it is if the problem arises. Personal tip, I like to add neem to my cleaning products so when I clean the walls and room it has the neem oil on the area still, keeps me from usually having to use anything else throughout my growth period and ive done it for years, seems to do the job. I dont like spraying anything onto my plants unless the problem presents itself. I do however spray it down with water to clean up the stomata and dirt occasionally, and occasionally spray up a real light AACT to keep my friendly bacterias in check.