Making THC pills

7mend07SweetnSticky

Well-Known Member
Ok I went back and reread the post but I still don't unsterstand why not to use it? I thought it made the coconut oil and bho mix better?
 

qwizoking

Well-Known Member
Lol the epitome of laziness, i took a quote from me...where the first half i didnt even feel like explaining.
lecithin.......
"In the pharmaceutical industry, it acts as a wetting, stabilizing agent and a choline enrichment carrier, helps in emulsifications and encapsulation, and is a good dispersing agent. It can be used in manufacture of intravenous fat infusions and for therapeutic use.

is an excellent emulsifier. In aqueous solution, its phospholipids can form either liposomes, bilayer sheets, micelles, or lamellar structures, depending on hydration and temperature."

sorry not in an explaining kind of mood today ^from wiki
heres a quout from my coconut oil thread. Why we use coconut
"....Now Medium-chain triglycerides (MCTs) are medium-chain (8 to 10 carbons, kinda 6-12)

In the digestive system MCTs are broken down into individual fatty acids (MCFA). Unlike other fatty acids, MCFA are absorbed directly from the intestines into the portal vein and sent straight to the liver where they are, for the most part, burned as fuel much like a carbohydrate. In this respect they act more like carbohydrates than like fats.

Other fats require pancreatic enzymes to break them into smaller units. They are then absorbed into the intestinal wall and packaged into bundles of fat (lipid) and protein called lipoproteins. These lipoproteins are carried by the lymphatic system, bypassing the liver, and then dumped into the bloodstream, where they are circulated throughout the body. As they circulate in the blood, their fatty components are distributed to all the tissues of the body. The lipoproteins get smaller and smaller, until there is little left of them. At this time they are picked up by the liver, broken apart, and used to produce energy
MCTs do not require bile salts for digestion and therefore, passively absorbed by the intestinal tract into the blood stream where they are used for energy.. of course a bit simplified but basically faster onset and less degradation occurs.
Rich sources of MCTs include palm kernel oil, coconut oil and camphor tree drupes."


now an emulsion doesnt help anything we want it all dissolved in, it would be great in salad dressing though. we put it in a carrier to lower polarity and increase efficiency..
thc has a logp of about 7
In practice optimum colonic is 1.32, intestinal is 1.35, oral 1.8, Cns 2, percutaneous at 2.6 and sublingual 5.5
Shorter chain triglycerides have a much lower polarity holding less in suspension and not being absorbed as quickly
an emulsion encapsulates..we dont want a suspension of cannabinoids. to make use of the coconut we want it dissolved in solution-not suspension.. it doesnt need help to be dispersed evenly this is the definition of a solution -homogenous.
All from a previous conversation on lecithen

You want to heat the oil and saturate it slowly with your hash concentrate
 
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7mend07SweetnSticky

Well-Known Member
If transdermal mean for use on the skin. I say its both. I want to use it for canna caps but I keep some around for its pain relieving quality. I used it on a bad burn and had no pain in the morning. But making it for canna caps for my insomnia
 

qwizoking

Well-Known Member
Hmm if its a dual purpose kinda deal thats the best carrier to use i suppose. When ready to use topically you could add something like dmso ethanol or propylene glycol. Normally i would suggest something like unrefined sunflower oil as a carrier and 5-10% etoh or pg.
 

7mend07SweetnSticky

Well-Known Member
I have tincture made with 75.5% ever clear and topical made with coconut oil. But from what I've gathered either can be used for both since you have already decarb'd your material already. Although coconut oil does absorb better through the skin than ethanol.
 

qwizoking

Well-Known Member
Well ethanol absorbs through the skin quite well and acts as a permeation enhancer removing the outer lipid barrier and proteins. But can be a skin irritant, drying, causing dermatitis and whatnot. A small amount is good. I generally suggest 5-10% as that still promotes healthy skin and does increase permeation.
Things like dmso pg and etoh are what i typically use being that they are pretty small molecules and have a lower polarity helping slide the bulky thc through the skin, remember that logp, the partition coefficient is very important... And it still migrates from that base. Coconut oil doesnt have particularly high flux rates but is great internally, not that it cant be used dont get me wrong but an unsaturated fatty acid is a better carrier.
 

7mend07SweetnSticky

Well-Known Member
I made two different types of pills. First I made the 150mg decarbed bho then decided to take one with a few friends for a test trial but we had been smoking a lot before so we didn't expect much. About 20-30 minutes in you can definitely feel the slight body high. Me having a knee injury made it feel much more relaxed during this point. Gradually the high intensifies as you relax and sit down. I was making the 130mg capsules and noticed the high had moved to my eyes as they got lazy and heavy. I took another one after finishing the 130's and I'm chill as hell now. no pains whats so ever.
Hey bro what formula did you use to calculate the pills milligram value?
 

GhostBud420

Well-Known Member
i really didn't use a formula... kinda trial and error. but if i remember correctly the ratio to get 150mg was 6.0g decarbed wax to 2.5-3g coco oil. Thats in the "0" size capsules.
 
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