Entactogens that can be made by Aminizing your Kitchen's Spice Cabinet

Finshaggy

Finshaggy

Well-Known Member
If you have not read PIHKAL over and over and over in actual book form, then you may not have noticed this.
Sasha mentions the Magical Half Dozen, which is 2C-I, etc
He mentions the 10 Classic Ladies, which is Florence, Ganesha, etc.

But he also mentions that it may be possible to create Molecules using your own liver by turning different enzymes on and off. Then on one of the recipes he gives you a list of all the Phenethylmaines that can be found in your Kitchen's Spice Cabinet, and then throughout PIHKAL he gives you the recipes for each of those Phenethylamines. He says that they just need to be Aminized, either in your liver or in a lab, and they will become active. This theory has been proven by what is now called Oilahuasca. If you mix different things together you can get different effects from different Molecules, it is based on the idea of Pro-Drugs and CYP450 Enzymes (Similar to MAOs which are effected by MAOIs). Some people have reported Psychedelic effects from Mixing just Coffee, Almond, Cinnamon, Vanilla and Nutmeg.



This is similar to how Saffrole, from Sassafras, can be used to make MDA or Ecstasy.
 
Finshaggy

Finshaggy

Well-Known Member
Procedure, in plain English:

Pepper would be made into a tea. Solids filtered out.

Then you would get some Anise Oil, B9 or Valerian Root (of Chinese Origin)

So that is your Pepperidine, and you activators. Now you need your Enzyme Inhibitors. You can add L-Lysine, but it is not necessary.

Vanilla and Cinnamon work, pick one or both. You also need the Aldehyde structure from one of these.

Next. German Chamomile, Cayenne Pepper Capsules or Tangerine Skin extract/capsules

Then
Almond extract, Anise Oil (if you already had it), Cinnamon, Lemon peel oil, Lime peel oil, or a cigarette or nicotine gum if you can't find anything else.

Then
CBD, Echinacea Purea, Pomegranate, Pummelo, or Calamus Oil.

Then
Clove oil, Catechin, Dill seed Oil or Goldenseal.

Then Kudzu or Glycerin or Caffeine

Not all of these things are neccisarry, but if you do 1 thing in each list, you should get very strong effects from whatever you take.

The best thing to take is Sweet Basil Extract, in it's pure form, it is known as Methyl Chavicol.

Take all that other stuff like 30 minutes to an hour before the Basil Extract, and redose the B9, Anise or Valerian root to keep the effects going without taking more.
 
Finshaggy

Finshaggy

Well-Known Member
Myristicin Extract, which is made from Nutmeg, can also be used in place of Methyl Chavicol from Basil.
 
Finshaggy

Finshaggy

Well-Known Member
The effects can range from Ecstasy like to Mescaline like, depending if you do it kind of right or all right.
 
Finshaggy

Finshaggy

Well-Known Member
Graviola- 5-HT1a Agonist
Black Cohosh- 5-HT1A, 5-HT1D & 5-HT7 Binding
C. Foetida L.- 5-HT1A Agonist
Yokukansan- 5-HT1A Agonist
DMT hits all of these, and can be found in tons of plants.

Black Cohosh- 5-HT1D
maybe Rhodiola rosea, Albizia lebbeck & Albizia julibrissin.

5-HT1 Receptor Agonists:
Turmeric, Ginger, Ginko Bilboa, Lemon Essential Oil, Rauwolfia, Valerian, Yohimbe

Elmicin & Myristicin (in Nutmeg)- 5-HT2A Agonist
Estragole (in Sweet Basil)- 5-HT2A Agonist
Safrole (in Sassafras)- 5-HT2A Agonist

Cinnamon Bark- CYP2A6 & CYP2E1 Inhibitor (It will deplete your liver's Glutithione) Taken 1 Hour before Allybenzene,
Clove Leaf- CYP2C9, CYP3A4, CYP1A1 & CYP1B1 Inhibitor
German Chamomile- CYP1A2 Inhibitor (Caffeine may also do this)
GoldenSseal & Echinacea purpurea very effectively do the same thing.
Black seed oil, 50% EGCG, Valerian root oil, Pomegranate, Vitamin B9, 40% Ellagic extract, Rooibos 20% Gallic acid extract, Rutin, B3 & Kudzu

AllylBenzenes
Anethole, Apiol, Asarone, Carpacin, Chavibetol, Chavicol, Dillapiole, Eugenol, Isoeugenol, Isosafrole, Methyl Eugenol, Methyl Isoeugenol,

since Cinnamon is a Phenylpropanoid, and Phenylpropanoids are made from Phenelalamine, and people who took Phenelalamine claim to get better results. I decided to post a list of Phenylpropanoids also.
Caffeyl Alcohol, Cinnamaldehyde, Cinnamyl alcohol, alpha-Cyno-4-hydroxycinnamic acid, Ethyl Cinnamate, Lignin, 2,4-Methlenedioxypropiophenone, Neoflavonoids, Nordihydroguaiaretic acid, Phenylpropanoic acid, Phloretic acid, Rhododendrin & Suberin.

Star Anise Extract or B9 for CYP2C9 Induction

Most important things:
CYP2C9 Induction
Alcohol Dehydrogenase Induction
Aldehyde Dehydrogenase Inhibition
Piperidine and or Dimethylamine Supplementation
Methyl from foods
Exercise or compounds that produce effects like exercise

Less important, but still factors:
SSAO Inhibition (Caffeine, Phenethylamine, Phenelalamine, Tryptamine)
MAO-A Induction
MAO-B Induction
NDMA Antagonism
Prolactin Inhibition
 
Finshaggy

Finshaggy

Well-Known Member
Indagrow said:
Have you tried any of this... What's a lethal dose?
Click to expand...
There are no established doses as far as I know, and I tried it once but I did not have all the materials and I felt a stimulant, light MDMA type feeling, but just a buzz, not full blown. I took Piperidine, Clove, German Chamomile, Kudzu and Basil. And I was not exactly sure what dosage to take so I kept it low. But there was a definite noticeable effect.

You can find other people's anecdotes about how much they have taken, but there aren't established doses yet.
 
Finshaggy

Finshaggy

Well-Known Member
And doctors are hardly even aware of these effects. The only time a doctor will talk about anything even close to this is when they tell people taking Liver medication not to drink Grapefruit juice because it might kill them. And the reason is because some liver medications break down too well and must be taken in massive doses 8g+ but if you drink Grapefruit juice your body will not break it down as well and you may end up getting the whole 8g+
 
Finshaggy

Finshaggy

Well-Known Member
For more information look up Oilahuasca, and share any new info or experiences here. This is probably the most through guide about what plants can be used.
 
Finshaggy

Finshaggy

Well-Known Member
Also, I have not tried this. There is a structure very similar to Propofol in Thyme called Thymol, but it is broken down in the stomach. So it may be possible to use Thyme extract and digest it like Propofol.

And according to Wikipedia
Thymol has been shown to act as a positive allosteric modulator of GABAa in vitro.
 
Finshaggy

Finshaggy

Well-Known Member
Also, for anyone who is worried about depleting your Glutithione levels in your liver. Just have some Tumeric handy and take it when you are done, the levels will go back to normal.

And this stuff all seems kind of extreme when you are reading it not in plain English, but these are Herbs that everyone eats every day, and these effects happen to them every day. They just don't add an allylbenzene to get the psychoactive effects.
 
Finshaggy

Finshaggy

Well-Known Member
If you have ever specifically drank or ate something because it was an Anti-Oxidant, then you have already been doing this on purpose, and you didn't even know.
 
Finshaggy

Finshaggy

Well-Known Member
The most simple mixture that anyone has ever posted with reported effects, and they said that they did this on accident, was Coffee, Almond, Cinnamon, Vanilla and Nutmeg.

Everyone should at least try that.
 
vostok

vostok

Well-Known Member
Done my time with Ms Nutmeg

we parted gracefully

after a 3 day lsd type trip

and several pounds lighter ...ll
 
Finshaggy

Finshaggy

Well-Known Member
The first person to actually get in to this stuff, after Sasha theorized it, said that he got interested when he noticed that Elimicin and Mystricin are inactive when taken alone, but when taken together in Nutmeg they produce the drunk nauseous feeling with the slight psychedelic effects, which is what happens when you take nutmeg alone in large doses. So he started trying to figure out what Elimicin and Mystericin were, and then found out about CYP450 Enzymes, so read about them on PubMed. Made a short guide, and then people started trying it and found different things that worked the best. And eventually got the effects to the strength of Mescaline.
 
Finshaggy

Finshaggy

Well-Known Member
And I found out about it when I was making a list of plants that hit different Serotonin/5-HT receptors, so I added what I was doing to what they were doing.

Finshaggy said:
Graviola- 5-HT1a Agonist
Black Cohosh- 5-HT1A, 5-HT1D & 5-HT7 Binding
C. Foetida L.- 5-HT1A Agonist
Yokukansan- 5-HT1A Agonist
DMT hits all of these, and can be found in tons of plants.

Black Cohosh- 5-HT1D
maybe Rhodiola rosea, Albizia lebbeck & Albizia julibrissin.

5-HT1 Receptor Agonists:
Turmeric, Ginger, Ginko Bilboa, Lemon Essential Oil, Rauwolfia, Valerian, Yohimbe

Elmicin & Myristicin (in Nutmeg)- 5-HT2A Agonist
Estragole (in Sweet Basil)- 5-HT2A Agonist
Safrole (in Sassafras)- 5-HT2A Agonist

Cinnamon Bark- CYP2A6 & CYP2E1 Inhibitor (It will deplete your liver's Glutithione) Taken 1 Hour before Allybenzene,
Clove Leaf- CYP2C9, CYP3A4, CYP1A1 & CYP1B1 Inhibitor
German Chamomile- CYP1A2 Inhibitor (Caffeine may also do this)
GoldenSseal & Echinacea purpurea very effectively do the same thing.
Black seed oil, 50% EGCG, Valerian root oil, Pomegranate, Vitamin B9, 40% Ellagic extract, Rooibos 20% Gallic acid extract, Rutin, B3 & Kudzu

AllylBenzenes
Anethole, Apiol, Asarone, Carpacin, Chavibetol, Chavicol, Dillapiole, Eugenol, Isoeugenol, Isosafrole, Methyl Eugenol, Methyl Isoeugenol,

since Cinnamon is a Phenylpropanoid, and Phenylpropanoids are made from Phenelalamine, and people who took Phenelalamine claim to get better results. I decided to post a list of Phenylpropanoids also.
Caffeyl Alcohol, Cinnamaldehyde, Cinnamyl alcohol, alpha-Cyno-4-hydroxycinnamic acid, Ethyl Cinnamate, Lignin, 2,4-Methlenedioxypropiophenone, Neoflavonoids, Nordihydroguaiaretic acid, Phenylpropanoic acid, Phloretic acid, Rhododendrin & Suberin.

Star Anise Extract or B9 for CYP2C9 Induction

Most important things:
CYP2C9 Induction
Alcohol Dehydrogenase Induction
Aldehyde Dehydrogenase Inhibition
Piperidine and or Dimethylamine Supplementation
Methyl from foods
Exercise or compounds that produce effects like exercise

Less important, but still factors:
SSAO Inhibition (Caffeine, Phenethylamine, Phenelalamine, Tryptamine)
MAO-A Induction
MAO-B Induction
NDMA Antagonism
Prolactin Inhibition
Click to expand...
 
Finshaggy

Finshaggy

Well-Known Member
When people say X Country is committing Human Rights Violations, this is where that comes from.

UN Universal Declaration of Human Rights
http://www.un.org/en/universal-declaration-human-rights/

Article 18
Everyone has the right to freedom of thought, conscience and religion; this right includes freedom to change his religion or belief, and freedom, either alone or in community with others and in public or private, to manifest his religion or belief in teaching, practice, worship and observance.

Article 27
(1) Everyone has the right freely to participate in the cultural life of the community, to enjoy the arts and to share in scientific advancement and its benefits.
(2) Everyone has the right to the protection of the moral and material interests resulting from any scientific, literary or artistic production of which he is the author.
 
Finshaggy

Finshaggy

Well-Known Member
All inhibitors of oxidative 17bHSD2 will prevent activation of allylbenzenes. This enzyme must be induced, not inhibited. It's the single most important enzyme to induce. If oxidative 17bHSD2 is not functioning, allylbenzenes cannot produce psychedelic activity. Naringenin also potently inhibits 17bHSD2. Grapefruit contains large amounts of naringenin, and also prevents the psychedelic action of allylbenzenes if taken before allylbenzenes. Inhibition lasts approximately 4-8 hours.

Here's a list of all known 17bHSD2 inhibitors that should be avoided 4-8 hours prior to using allylbenzenes:
•Quercetin and all food or supplements containing large amounts of it.
•Apples (0.0263% quercetin)[6]
•Cabbage (0.01% quercetin)[6]
•Cranberry (0.025% quercetin)[6]
•Evening-Primrose (20% quercetin)[6]
•Galangin and all food or supplements containing large amounts of it.
•Garlic (0.02% quercetin)[6]
•Grapefruit (contains naringenin, kaempferol, galangin, and quercetin)
•Himalayan Mayapple (1.2% quercetin)[6]
•Kaempferide and all food or supplements containing large amounts of it.
•kaempferol and all foods that contain large amounts it.
•Mayapple (5% quercetin)[6]
•Naringenin and all food or supplements containing large amounts of it.
•Neem (0.1% Quercetin)[6]
•Oats (0.031% Quercetin)[6]
•Onions (4.81% quercetin).[6]
•Orange (4.58% naringenin)[6]
•Tea (10-25 mg/L quercetin, 6.3-17 mg/L kaempferol [7]).[6]
•Tomato (contains kaempferol, naringenin)
•Yuzu (contains naringenin)
 
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