Pandemic 2020

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DIY-HP-LED

Well-Known Member
Vaccinated people with the sniffles aren't likely to line up for testing.
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Dr. Scott Gottlieb estimates up to 1 million Americans infected with Covid daily as delta spreads

KEY POINTS
  • The highly transmissible delta variant is driving a surge in Covid cases across the U.S.
  • However, Dr. Scott Gottlieb told CNBC on Friday he believes the coronavirus is significantly more widespread in the U.S. than official case counts reflect.
  • “I wouldn’t be surprised if, on the whole, we’re infecting up to a million people a day right now,” the former FDA chief said.
Dr. Scott Gottlieb told CNBC on Friday he believes the coronavirus is significantly more widespread in the U.S. than official case counts reflect as the highly contagious delta variant sweeps the nation.

“I wouldn’t be surprised if, on the whole, we’re infecting up to a million people a day right now, and we’re just picking up maybe a 10th of that or less than a 10th of that,” the former Food and Drug Administration commissioner said in an interview on “Squawk Box.” Gottlieb now serves on the board of Covid vaccine maker Pfizer.

The current seven-day average of new daily coronavirus cases in the U.S. is roughly 67,000, according to a CNBC analysis of Johns Hopkins University data. That’s up 53% compared with a week ago, as the country grapples with a surge in new infections driven largely by delta, first discovered in India and now the dominant variant in the U.S.

“What it reflects is a reality where you have a highly transmissible variant that’s widely spread across the U.S. right now that’s spreading mostly in a population that’s either vaccinated and developing mild symptoms or no symptoms at all; or spreading in a younger population that’s also less likely to develop symptoms because they’re younger, healthier,” Gottlieb said, when asked by “Squawk Box” co-host Andrew Ross Sorkin how the physician arrived at his “staggering” estimation of 1 million new infections a day.

“Most of the spread and most of the people who are showing up in the hospital are younger people. If that’s where the infection is occurring, then there must be a lot more infection underneath the small numerator that’s showing up in the hospital,” added Gottlieb, who led the FDA from 2017 to 2019 in the Trump administration. He’s become a closely watched voice during the pandemic, routinely appearing on CNBC and other media outlets to offer his analysis on the health crisis.

The highest seven-day day average of new Covid cases recorded in the U.S. was roughly 251,000 on Jan. 8, according to CNBC’s analysis. Case counts had dropped off dramatically in the spring as the country’s vaccination campaign picked up speed.

But in recent weeks, as U.S. cases again started to accelerate, Gottlieb has said a large number of coronavirus infections were likely going unreported, partly because the testing landscape is different now than at previous stages in the pandemic. In the early days, Gottlieb suggested the actual case counts were much higher than official tallies due to scarce testing resources.

Now, he has said it’s a different situation, where the discrepancy between case counts and true infection levels stems from people who remain asymptomatic or develop only mild symptoms not going to get tested. Additionally, Gottlieb previously told CNBC people can now complete at-home tests and those results are unlikely to make their way to health authorities and then show up in official case counts.

On Friday, Gottlieb reiterated his view that the U.S. is much further into the surge of delta-driven infections than others believe. “This delta wave will pass, probably at some point in September,” he predicted.

Gottlieb’s comments Friday came after The Washington Post and other media organizations, including CNBC, reported on a leaked Centers for Disease Control and Prevention document about the risks presented by the delta variant.

The public-health agency’s document, authenticated to CNBC by the U.S. agency, said the delta variant is as transmissible as chickenpox and suggested vaccinated people may be able to pass on the virus strain to others as easily as unvaccinated individuals.

The studies and data included in the document were seen as key factors in the CDC reversing course on masks earlier this week. The agency now recommends all people, even those who are vaccinated, wear face coverings indoors in areas with high transmission.
 

CunningCanuk

Well-Known Member

Vaccination is not enough by itself to stop the spread of variants, study finds

CNN —
Vaccination alone won’t stop the rise of new variants and in fact could push the evolution of strains that evade their protection, researchers warned Friday.

They said people need to wear masks and take other steps to prevent spread until almost everyone in a population has been vaccinated.

Their findings, published in Nature Scientific Reports, support an unpopular decision by the US Centers for Disease Control and Prevention to advise even fully vaccinated people to start wearing masks again in areas of sustained or high transmission.

“We found that a fast rate of vaccination decreases the probability of emergence of a resistant strain,” the team wrote.

“Counterintuitively, when a relaxation of non-pharmaceutical interventions happened at a time when most individuals of the population have already been vaccinated, the probability of emergence of a resistant strain was greatly increased,” they added.

“Our results suggest that policymakers and individuals should consider maintaining non-pharmaceutical interventions and transmission-reducing behaviors throughout the entire vaccination period.”

“When most people are vaccinated, the vaccine-resistant strain has an advantage over the original strain,” Simon Rella of the Institute of Science and Technology Austria, who worked on the study, told reporters.

“This means the vaccine resistant strain spreads through the population faster at a time when most people are vaccinated.”

But if so-called non pharmaceutical interventions are maintained – such as mask use and social distancing – the virus is less likely to spread and change. “There is a chance to remove the vaccine resistant mutations from the population,” Rella said.

The team used a mathematical model to predict these changes, but their findings follow what is known about the epidemiology of viruses and what’s known as selective pressure – the force that drives any organism to evolve.

The findings suggest that policymakers should resist the temptation to lift restrictions to celebrate or reward vaccination efforts.

This is likely to be especially true with a more transmissible variant such as the Delta variant, said Fyodor Kondrashov, also of the Institute of Science and Technology Austria.

“Generally, the more people are infected, the more the chances for vaccine resistance to emerge. So the more Delta is infectious, the more reason for concern,” Kondrashov told reporters.

“By having a situation where you vaccinate everybody, a vaccine-resistant mutant actually gains a selective advantage.”

On Tuesday, the US CDC altered its guidance on mask use. The CDC said earlier this year that fully vaccinated people are very safe from infection and can take off their masks in most situations.

Now, it says even fully vaccinated people can sometimes catch the virus and if they catch the Delta variant, they are just as likely to infect someone else as an unvaccinated person would be. It advised everyone in areas of high or sustained virus transmission to wear masks when around others.

Many GOP politicians have derided the new advice. On Thursday, Mississippi Gov. Tate Reeves called it “foolish.”

While the CDC was not thinking about the evolution of variants, Kondrashov said people skeptical of maintaining vigilance should be.

“The individual who already vaccinated and putting on a mask should not think this is pointless but should think that there is a vaccine resistant strain running around,” he said.

“By preventing spread of vaccine resistant strains, you are preventing evolution of this virus,” he added.

“We have two tools in our toolbox to do this. One is non pharmaceutical interventions such as mask wearing and the whole shebang, and the second is vaccines. From an evolutionary perspective, what is necessary to reduce this (spread) is to vaccinate as many people as possible as fast as possible and across the globe.”
Sadly, this is going to be with us a long, long time.
 

DIY-HP-LED

Well-Known Member

CDC mask decision followed stunning findings from Cape Cod beach outbreak
A group of vaccinated beachgoers changed our knowledge of the delta variant.

A week after the crowds descended upon Provincetown, Massachusetts, to celebrate the Fourth of July -- the holiday President Joe Biden hoped would mark the nation's liberation from COVID-19 -- the manager of the Cape Cod beach town said he was aware of "a handful of positive COVID cases among folks" who spent time there.

"We are in touch with the Health Department and Outer Cape Health Services and are closely monitoring the data," Alex Morse told reporters.

The announcement wasn't unusual with roughly half of the country still unvaccinated and flare-ups of the virus popping up in various states.


But within weeks, health officials seemed to be on to something much bigger. The outbreak quickly grew to the hundreds and most of them appeared to be vaccinated.

MORE: Vast majority of ICU patients with COVID-19 are unvaccinated, ABC News survey finds
As of Thursday, 882 people were tied to the Provincetown outbreak. Among those living in Massachusetts, 74% of them were fully immunized, yet officials said the vast majority were also reporting symptoms. Seven people were reported hospitalized.

The initial findings of the investigation led by the Massachusetts Department of Public Health, in conjunction with the Centers for Disease Control and Prevention, seemed to have huge implications.

Before Provincetown, health officials had been operating under the assumption that it was extraordinarily rare for a vaccinated person to become infected with the virus. And if they did, they probably wouldn't end up passing it on to others, such as children too young to qualify for the vaccine or people who were medically vulnerable.

The idea that vaccines halt transmission of the virus was largely behind the CDC's decision in May suggesting vaccinated people could safely go without their masks indoors and in crowds, even if others were unvaccinated.

But that assumption had been based on studies of earlier versions of the virus. Delta was known for its "hyper-transmissibility," or as one former White House adviser put it "COVID on steroids."

"What has changed is the virus," said Dr. Anthony Fauci, the nation's top infectious disease expert and Biden's chief medical adviser.

When a vaccinated person gets infected with delta -- called a "breakthrough infection" -- "the level of virus in their nasopharynx is about 1,000 times higher than with the alpha variant," Fauci said in an interview Wednesday with MSNBC.

All indications now are that the Provincetown outbreak investigation is among the pieces of new evidence behind the CDC's decision to ask Americans to once again put on their masks indoors, even if they are vaccinated.

"In recent days I have seen new scientific data from recent outbreak investigations, showing that the delta variant behaves uniquely differently from past strains of the virus that causes COVID 19," CDC Director Rochelle Walensky told reporters Tuesday announcing the new recommendations.

"Information on the delta variants from several states and other countries, indicate that in rare occasion some vaccinated people infected with a delta variant after vaccination may be contagious and spread the virus to others," she added. "This new science is worrisome and unfortunately warrants an update to our recommendation."

When asked to release the new evidence, the CDC said more details would be released on Friday.

But Walensky hinted that the biggest driver was new unpublished research on a person's "viral load" -- the amount of virus in a person's nasal passages -- being considerably high even after being vaccinated with a U.S.-authorized vaccine.

"What we've learned … is that when we examine the rare or breakthrough infections and we look at the amount of virus in those people, it is pretty similar to the amount of virus in unvaccinated people," she said.
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DIY-HP-LED

Well-Known Member
Sadly, this is going to be with us a long, long time.
There is cause for optimism in the longer term, both medically and politically. It's hammering the Trumpers and antivaxxers the hardest now with delta and the free ride they've been having is over. It is also dividing and diminishing the republican party and decreasing their odds of winning in 2022. Fewer will die with this wave, but more might have their attitudes adjusted by the ride covid provides. Meanwhile 90% of seniors are vaccinated and watching, covid already cut deeply into GOP support among seniors, besides many like old uncle Joe and his steady hand.

There are other vaccines and booster shots in the works or in trials, including a vaccine pill by the end of the year along with several very effective broad spectrum antibodies. Then there are the antiviral drugs under trial now and even better supportive therapies. Another good thing is antibodies can act as a temporary vaccine for the immunocompromised and offer up to 3 months protection.

Everybody who is unvaccinated and many who are, will probably get delta by October, if it is infecting a million people a day.
 

captainmorgan

Well-Known Member
Look on the bright side, if not for the pandemic Stinky could have been reelected. Get vaccinated and wear N95 in public and you should stay out of the hospital. Just have to be patient, a few more waves and the tRUmptard problem will solve itself.
 

xtsho

Well-Known Member
Because he was/is a fucking idiot & anyone that supports/makes excuses for/defends him is also a fucking idiot.
Rebuttal time @Plutonium
Go for it :)
Well in all fairness he did bring up the potential of using bleach intravenously.

"And then I see the disinfectant, where it knocks it out in one minute. And is there a way we can do something like that, by injection inside or almost a cleaning,"

That right there proves trump is smarter than all of the Doctors. He's also the best business man which is why all of his businesses end in bankruptcy.

I just don't understand why anyone wouldn't be part of the MADA movement. Make America Dumb Again.
 

captainmorgan

Well-Known Member
I'm just realistic, I read that 30+ year study on the lack of long term immunity from human corona viruses early on in the pandemic. And I haven't been conditioned to believe in magical thinking by some church run by conmen.
 

DIY-HP-LED

Well-Known Member
Until a new variant evades vaccines
They have developed other vaccine approaches that entrap the virus in evolutionary terms by going after multiple fundamental processes. This spike based vaccine is a quick and dirty solution, other more elegant and effective fixes are in the works along with therapeutics. Make no mistake though, we are in a race with the variants, but I believe we are gaining the upper hand.

In Canada I expect delta will drive voluntary vaccine rates up to near 90% in many places. In America, when vaccines come out of EUA, it will have the biggest impact with private and state mandates. Covid and it's long term implications are gonna cost health insurance companies a fortune and they are not gonna pay for stupidity any longer than they have to. Most Americans get their healthcare insurance through employers and they will mandate it for staff or pay a fortune in insurance premiums. When employers colleges and schools mandate vaccines compliance is in the high 90%s. Many experts figure EUA will end around September for the Pfizer mRNA vaccine at least.
 

Dr.Amber Trichome

Well-Known Member
They have developed other vaccine approaches that entrap the virus in evolutionary terms by going after multiple fundamental processes. This spike based vaccine is a quick and dirty solution, other more elegant and effective fixes are in the works along with therapeutics. Make no mistake though, we are in a race with the variants, but I believe we are gaining the upper hand.

In Canada I expect delta will drive voluntary vaccine rates up to near 90% in many places. In America, when vaccines come out of EUA, it will have the biggest impact with private and state mandates. Covid and it's long term implications are gonna cost health insurance companies a fortune and they are not gonna pay for stupidity any longer than they have to. Most Americans get their healthcare insurance through employers and they will mandate it for staff or pay a fortune in insurance premiums. When employers colleges and schools mandate vaccines compliance is in the high 90%s. Many experts figure EUA will end around September for the Pfizer mRNA vaccine at least.
Federal US postal union is so pissed about the new vaccine mandate. There are so many asshole anti vaccine postal workers . I remember when I was living in Oklahoma and this one postal worker never wore a mask working at the front desk even in the prime of the pandemic . Oh I would love to see her now, that fucking cunt.
 
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