As well as the danger of a user hurting themselves while in a state of delirium, there is also the toxicity of scopolamine and atropine. Both of these chemicals are poisons and have been used for many years in murders and suicides.
Atropine increases the firing of the Sinoatrial Node (SAN) and the conductivity of the Artioventricular Node (AVN) in the heart. This means that the wave of excitation that makes a users heart beat, will happen more regularly and be passed around the heart at a faster rate. This could result in cardiac arrest. In addition to this it opposes information sent along the Vagus nerve, which conveys information about the state of the viscera (organs such as the heart and others lower in the abdomen). This means there is danger of damage to these organs.
Because of the unknown quantity of tropane alkaloids in each Datura plant, a quantity for overdose is going to be hard to predict. To reduce chance of overdose start very small and work your way up to larger doses. Remember if using another plant the dosage will be different from last time. Effects for most people will begin within an hour of consumption, however it is important to remember that in 25% of the population scopolamine is absorbed by the brain slower and can take up to 13 hours.
A SITTER IS ALWAYS NEEDED!
