XTC and brain damage

canndo said:

I know, I know I promised I wouldn't say this again but...



Dude, don't you know the stuff puts holes in your brain?

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LoL, oh you!

Wow, different subject but i guess cause ive grown up near the beach i just cant belive people wouldnt have been there in years or even at all!!

We used to drop at a beach near my house, sucluded as so had the while thing to ourselfes. Used to have masive bon fires and party hard. Man those were the days!

I wish you all thw best in getting better

I hope your jokig about the holes in your brain? Because the guy that did thos tests got found outthat he made them up and admitted to it when no other people could get the same results with the same test. He aparently used methamphetamine instead of mdma.

Over usages of X does put holes in the occipital lobe region of the brain, i.e. the lower back portion, and shrinks your hippocampus as well; seeing tracers and talking your ass off aren't side effects, that's the MDMA over-exciting neurons in the parts of the brain I just mentioned. Like most drugs, moderation is key; long term use will result is major long term memory loss, though cognitive skills aren't drastically impaired. Keep in mind, once your hippocampus bites the dust, you'll start showing traits of Alzheimer. Save what little brain cells you have left and stick to the kind bud.

well guess i wasnt supposed to eat ne rolls cause my ride fell through lol o well fuck im baked

So do you have evidence to back that claim up? Only study ive found that said it caused holes in the brain was debunked years ago. Ive read alot of peer reviewed journals.

Links to follow.........

Pluss that whole paragraph sounds like it was lifted from a govenment anti drug add from the 1990's

http://www.erowid.org/chemicals/mdma/mdma_neurotoxicity3.shtml

MDMA Brain Scans Showing Neurotoxicity DiscreditedSeveral Articles Highlight Questionable Scienceby Erowid, April 2002​

In another blow to the US Government's credibility as drug information provider, the Johns Hopkins brain scans which have been used to 'prove' MDMA causes brain damage have been called flawed by independent researchers and editors of the magazine New Scientist.

• New Scientist challenges the ethics and reliability of science-for-politics
• New Scientist documents errors and data obfuscation in compromised reasearch
• Toronto-based researcher Stephen Kish questions reliability of available PET scan data
• Other top PET scan experts criticize the PET scan data
• NIDA's credibility suffers once again

Under the cover story "E is for Evidence", the British science-oriented magazine "New Scientist" published a set of articles and editorials related to this topic in April 2002, denouncing the use of the questionable scientific data in the war on ecstasy consumption. There are several articles in the New Scientist, but most of them can be found following the links below.

The New Scientist article is a well-balanced, but critical, look at the issue of overstating the certainty of findings of brain damage in ecstasy users. "We are not saying that ecstasy is harmless to brain cells. It might not be. But the jury is still out. Which means scientists must resist the temptation to turn their always complex--and sometimes flawed--findings into simple scare stories in pursuit of grants and headlines."

It is refreshing to see a mainstream technical magazine publishing critiques of the science-for-politics which has compromised the credibility of government-sponsored science in the eyes of many. Historically, it has been left to fringe groups to criticize the fundamental system of peer-reviewed "science" and the often unscientific politics and economics which govern publication. The New Scientist describes how journal editors have joined in the War on Drugs by turning down articles which do not support the "anti-drug" view, including papers which report "no-effect" results.
What is most troubling, perhaps, is how often "Science" has been misappopriated for the moral crusade against recreational psychoactive use. The now debunked moral panics surrounding LSD and chromosome damage, 'reefer madness', cannabis and brain damage, "crack babies", and most recently the ecstasy 'holes in your head' campaign, have all come from premature, controversial, or invalid science foisted onto the public by overeager, overfunded Drug Warriors.


Stephen Kish's article in "Pharmacology, Biochemistry, and Behaviour" published in April, 2002 investigates the reliability of the PET brain scanning showing damage. He concludes that the studies completed to date include serious methodological flaws, huge variations between individuals tested, use of non-serotonin specific tests, lack of test-retest reliability data, and other invalidating assumptions about the types of tests used. He says that, based on the brain scan research to date, "it cannot be assumed that ecstasy exposure [causes] a chronic serotonin deficiency condition."
Another paper currently in the process of publication also examines the PET scans, showing that the serotonin binding levels recorded for even extremely heavy ecstasy users (estimated 500 mg average dose between 70 and 400 times) in the 1998 McCann & Ricaurte study were typical for controls in other studies using the same chemicals (ligands) and scanning techniques. As one PET researcher described to us, the Ricaurte team didn't have the necessary skills required to competently analyse the data. They were undertrained in the technically demanding field of PET Scanning and their results reflect both a lack of ability and a failure to notice when their results were coming back wrong.
The New Scientist and Pharmacology, Biochemistry, and Behaviour investigations of flawed research practices offer a breath of fresh air in the ongoing debate about ecstasy's effects on the brain. Perhaps better reporting and editorial leadership will emerge over time, in spite of the political pressures faced by peer-reviewed journals.

MISSPHOEBE said:

dude I discovered something......... a really great way to be high!
High on Life!
......... I realized that being 'straight is a High in and of itself........ without the need to smoke, drink or take any type of chemicals..... you become High On Life..........
The anger dissipates.........
The Memory returns................
U feel clear and cool and clean...............
Unfuzzy
It really is being High On Life! U have more energy! More motivation! More Happy Thoughts & More Happy Experiences..............
It is amazing I overlooked it for so long
Nature and Natures way is defo that way becoz it is the Best way
We were meant to dabble and enjoy and experiment but to be clean and clear is really the better experience of ALL!
and dude
Its FREE
and you don't need a dealer to get you some............
becoz its all YOU..........
* Like * Like * Like *

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hey im high as on life!! ive never been happier with who and where i am in my life than now.

i hardly take drugs anymore just a little bit of weed, but i truly have had the most amazing experiences on drugs and if i could go back and do it again i wouldnt change a thing

JQuick said:

I dont know if its a fact but from my experiences it does. I used to roll for sometimes a week at a time about a year ago and i did it for about a year strait. Would just stay awake for days on days rolling goin crazy. crash for like 2 days them wake up wit 2 pills. used to be insane. but my brain definitely suffered from this. i feel like i cant concentrate on anything, got some serious anger issues now and just cant feel happy. Does anyone know if excessive ecstasy use REALLY causes brain damage cause i wanna get to tha bottom of this.

This weekend ima roll for my last time, most likely, since im goin to tha beach. pickin up a ten pack tonight.

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Contrary to long-held opinion, ecstasy, the popular rave-culture drug, may not harm your brain.
This is according to one of the largest studies ever conducted on the illegal drug's effect on cognition, published last week in the journal Addiction.
Though former studies have concluded quite the opposite about the drug (technical name 3,4-Methylenedioxymethamphetamine, or MDMA) there's been concern that these conclusions were overstated and reached through faulty methods.
The latest research, a $1.8 million study funded by the National Institute on Drug Abuse (NIDA), set out to correct these methods by eliminating all other factors that could possibly contribute to mental impairment:
1) sleep deprivation and dehydration commonplace in rave culture,
2) previous habitual drug or alcohol use,
or 3) former cognitive damage for any reason.
After screening subjects for these factors (even testing hair samples to make sure they weren't lying about drug use) researchers whittled down the initial pool of 1,500 people to just 52 cognitively clean subjects, the Guardian reports.
John Halpern, lead researcher from the Harvard Medical School team, told Addition:Ecstasy is most commonly associated with the 1980s and 90s rave scene -- all-night dance complete with strobe lights and glow sticks to enhance the drug's effect. Ecstasy's symptoms include a feeling of euphoria, a heightened sense of intimacy and pleasure, and decreased anxiety. Negative side effects include blurred vision, and in rare cases overdoses can be fatal.

The common understanding, and certainly the argument from the anti-drug camp, has been that ecstasy can cause memory loss, pose a serious brain damage risk, and have long-lasting effects on behavior.
Researchers are quick to point out that despite the study's conclusion, ecstasy is still a dangerous drug. The illegal pills have no warning labels, and can contain a number of harmful contaminants.
Studies have also looked into MDMA-assisted psychotherapy as a possible treatment for post-traumatic stress disorder (PTSD). The idea is to provide at least a brief experience of what life feels like without the aftermath of trauma, to provide a state in which learning can occur..................

.....................info from.....................http://www.huffingtonpost.com/2011/02/20/ecstacy-doesnt-damage-the_n_825704.html

delvite said:

Contrary to long-held opinion, ecstasy, the popular rave-culture drug, may not harm your brain.
1) sleep deprivation and dehydration commonplace in rave culture,
2) previous habitual drug or alcohol use,
or 3) former cognitive damage for any reason.

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That would make sense. Didnt go to raves but partied like we were at one lol, didnt sleep and sometimes no water, alot of drinking and other shit, and alot of fighting