i have 4-70 gallon resevoirs and using an extra pump and running a length of hose to the bathroom, I pump it out, prop one end up on a piece of 2x4, pump till it won't pump out anymore then I use a hand bilge pump (available at plumbing or irrigation supply houses) to pump the rest out into a bucket, clean with my h2o2 solution and fill for re-use. All 4 get done on the same day (every 10th day) and take about three hours to change and clean thoroughly.
I do the same thing with my aerocloner which holds about 18 gallons, except when it is almost pumped out I just dump it by hand.