Ok well I know a clone can be cloned and the clones clone can be cloned and so on. So it is fine on that respect. With that said I have heard that the structure of a plant from seeds root system is a little different from that of a clone. Technically the plant from seed has a better connection from the roots to the top of the plant because of the seed having the one main tap root and the clones having a bunch of different roots. The plant from seeds top has a more direct connection with the root system because of this. But this in no problem unless the plant gets huge. Like I'm talking outdoor huge so indoors on a mother with a set root base in a pot shouldn't be a problem, but what do I know I never kept a mother long, just flower then after cloning. But I think your main pro for doing it from clone would be you get to see which plant is your favorite first. You can see what plants you like in veg but you wont get to see genes like calyx size, bud density, yield, feeding needs in flower, harvest times, and bud to leaf ratios. Unless your growing a very homogenous strain like an IBL mendo or something, then they should all be similar.