Medical Benefits Of Synthetic Canabinoids K2/Spice?

Jersey'sFinest

Active Member
I'm no scientist or professional, Bro, but judging from the fact that "Spice" and its brethren is made from a completely chemical compound sprayed onto foliage, my guess is that there are not any medicinal benefits. It has been proposed that shit like that even puts holes in your lungs over long term use.
Living in Michigan, why not get a card and grow yourself some nice organic medicine that is proven to have a positive effect on body and mind? Just my 2 cents.
 

Eulin

Member
I'm no scientist or professional, Bro, but judging from the fact that "Spice" and its brethren is made from a completely chemical compound sprayed onto foliage, my guess is that there are not any medicinal benefits. It has been proposed that shit like that even puts holes in your lungs over long term use.
Living in Michigan, why not get a card and grow yourself some nice organic medicine that is proven to have a positive effect on body and mind? Just my 2 cents.
Ya it's pretty obivous that the "spice" sold at gas stations and quickie marts does not have any medicial qualties, i'm talking about the specific chemicials (analogs) that are the active ingredient in the stuff. Alot of modern pharmaceuticals are based on synthetic versions of compounds found in nature. Often, the synthetic versions are preffered as they can be made without depending so heavily on the 'natural' supply chain.


LOL I dont use spice, you are damn right I have my card and some nice sour d :)
 

vilify

Well-Known Member
very little if any.

true medical benefits of naturals come from EVERYthing from that plant working together. that is why weed works better than marinol.

synthetics may prevent what u use them for, but what other harms are they causing in the process... Not worth it.
 

Eulin

Member
very little if any.

true medical benefits of naturals come from EVERYthing from that plant working together. that is why weed works better than marinol.

synthetics may prevent what u use them for, but what other harms are they causing in the process... Not worth it.
But that angle totally ignores the fact that most prescription drugs are based on synthetics. For Example I have an under active thyroid, my doctor prescribes me
levothyroxine, a synthetic form of thyroxine (Levothyroxine is also referred to as l-thyroxine). This is a synthetic form of a naturally occurring substance, thyroxine.

Thyroxine is available in its natural state, and in fact that is what used to be prescribed. Since the availability of levothyroxine, thyroxine has become the most popular and commonly prescribed thyroid hormone replacement drug.

It makes sense that if if something is beneficial in its natural state, that by understanding how it works components of such can be isolated and synthesized.

They did just bring 2pac back to life in a synthetic format after-all :)
 

vilify

Well-Known Member
there will be side effects either way, whether they are really harmful or not.

period
 

Eulin

Member
Thats true, but not true to the point of the thread.

Of course there are side effects with any drug natural or synthetic, harmful or harmless, that's an obvious fact.

I want to explore any potential medical benefits of Synthetic Canabinoids, specifically if they could replace medical marijuana - it's totally possible and that would suck!
 

OGEvilgenius

Well-Known Member
I think there is potential in these medically, but they are pretty dangerous substances and should be treated as such. The side effects may or may not make them viable as any form of treatment. I would say the most interesting path for research would be into neuroprotective qualities and the anti cancer properties. Maybe a full agonist will be more potent as an anti cancer drug than a partial? Or maybe the partial is better because there is no upper limit dosage... It's an interesting discussion for sure, but I wouldn't fuck with these things recreationally.
 

MacGuyver4.2.0

Well-Known Member
The U.S. Government has a patent dating back to 2003 on the 'synthetic' use of CBN/CBD compounds. (I'll stick to 100% natural thank-you) ;)
If you want to know more about the 'benefits' of synthesized junk simply use Google Patents and search for the following:

US Patent 6630507 titled “Cannabinoids as antioxidants and neuroprotectants” which is assigned to The United States of America, as represented by the Department of Health and Human Services.
 

Eulin

Member
If (when) science recognizes components in marijuana that have medicial properties they are for sure going to isolate them and synthesize them. That is how it works - if they found a compound in some rain-forest flower that gave old men hard-ons they would not cultivate the flower in greenhouses and process it into pills, they would re-create the naturally occuring compound and go from there.

That being said, follow that same line of logic with the the cultivation and distribution of medical marijuana. When science recognizes components in marijuana that have medicial properties they are for sure going to isolate them and synthesize them - potentially ending any reason for naturally grown medical marijuana. That is the real possibility I fear, is this a real possibility or am I taking this too far? (I know sometimes I do that)
 

vilify

Well-Known Member
i would agree with synthetics cannabinoids, but not how they are doing it with the ks/spice

if it was a pure cannibinoid, there are benefits. but they have to change the way they synthesize the chemical, so who knows what it really is at the time.

there are no side effects from naturals, argue smoking, but there are other ways of ingesting marijuana to avoid side effects of smoking.
 

Eulin

Member
you mean beside euthanasia? man that stuff is deadly poison its a synthetic drug that has no research to it, and i doubt i has any healing properties
It's not a deadly poison, its a synthetic canabinoid. It took a lot of research to synthesize it. Synthetic does not equal poison. You are probably wearing clothes with synthetic fibers right now.

The way synthetic canabinoids are being used currently is flakey and dangerous.

Looking at other synthetics they end up being superior to the natural compound that inspired it - for example Synthetic Oil used in cars, any high performance or mission-critical engine uses synthetic oil. Synthetic materials like kelvar are so good that they do not have any natural equivalents.

I'm thinking that if they get their act together with synthetic canabinoids the next logical step would be to apply it in the same way that Medical Marijuana is applied. That just ain't right, but its totally possible.

If Medical Marijuana emerges with marketable medicinal qualities you can bet your ass that drug makers will try to "get in on that" with a synthetic. They have done it with EVERY other drug out there.
 

vilify

Well-Known Member
It's not a deadly poison, its a synthetic canabinoid. It took a lot of research to synthesize it. Synthetic does not equal poison. You are probably wearing clothes with synthetic fibers right now.

The way synthetic canabinoids are being used currently is flakey and dangerous.

Looking at other synthetics they end up being superior to the natural compound that inspired it - for example Synthetic Oil used in cars, any high performance or mission-critical engine uses synthetic oil. Synthetic materials like kelvar are so good that they do not have any natural equivalents.

I'm thinking that if they get their act together with synthetic canabinoids the next logical step would be to apply it in the same way that Medical Marijuana is applied. That just ain't right, but its totally possible.

If Medical Marijuana emerges with marketable medicinal qualities you can bet your ass that drug makers will try to "get in on that" with a synthetic. They have done it with EVERY other drug out there.

The stuff you are referring to, that is used in spice/k2 is not the same as a synthetics cannabinoid. Those synthetics are Marijuana like chemicals, and not even close to the same as synthesizing THC, which like i stated earlier, is already being done.

Marinol -
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000403/
Nabilone -
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000398/

Wheras spice/k2 use JWH-018, JWH-073 JWH-200 and other variations of it
http://en.wikipedia.org/wiki/JWH-018

JWH effects the body entirely different than THC does.
 

polyarcturus

Well-Known Member
JWH effects the body entirely different than THC does.

so in other word its crack? srry to take this out of context but your saying it yourself, it does not work the same way as THC, i know first hand, that shit (posh) feels like being on crack. and the junkies i knew that where doing the SALT well they became literal crack heads(stealing, prostituting, scrapping ect)

now that not to say a medical laboratory somewhere couldn't find uses for it in low doses or wtfe but they wouldn't say smoke it thats unhealthy in itself. all im saying is the research that has been done has not been done on this new shit and they dropped it in the market like it was all good.

now we got people in my neighborhood breaking into house and stabbing a young girl sleeping on their couch till the police get there.
 

Eulin

Member
The stuff you are referring to, that is used in spice/k2 is not the same as a synthetics cannabinoid. Those synthetics are Marijuana like chemicals, and not even close to the same as synthesizing THC, which like i stated earlier, is already being done.

Marinol -
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000403/
Nabilone -
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000398/

Wheras spice/k2 use JWH-018, JWH-073 JWH-200 and other variations of it
http://en.wikipedia.org/wiki/JWH-018

JWH effects the body entirely different than THC does.
So these are just "chemicials" LOL

You seem confused, please read the links you supplied

or read the TL;DR version below:

In a nutshell Marinol and Nabilone are synthetic THC , which in fact does have commercial medical value

and JWH-018, JWH-073 JWH-200 and other variations are a synthetic cannabinoids, of which the medical value is in question
 

vilify

Well-Known Member
theres a difference between synthesizing THC as a whole, and parts of it.

JWH = synthesized analogues and metabolites of Δ[SUP]9[/SUP]-tetrahydrocannabinol (THC)
JWH = full agonist
THC = Partial agonist

did i say they were JUST chemicals? Look around you, everything is pretty much a "chemical".

they are fucking with nature. far beyond what they should be.
JWH's compound changes every week to remain legal.
There is a reason natural marijuana works better than marinol. There are 400+ compunds in the marijuana plant working together to balance what it does.

I am not confused in any way, but you sure seem to be.
Argue all you want, ive seen people get fucked up, and not in a good way, on spice, and never on marijuana.

The area of synthetics has been explored, and JWH isnt it.

"Looking at other synthetics they end up being superior to the natural compound that inspired it"
Theres a difference between synthetics you put and cars, and synthetics you put in your body. Synthetic medicine will never be better for you than naturals.
 

Eulin

Member
theres a difference between synthesizing THC as a whole, and parts of it.

JWH = synthesized analogues and metabolites of Δ[SUP]9[/SUP]-tetrahydrocannabinol (THC)
JWH = full agonist
THC = Partial agonist

did i say they were JUST chemicals? Look around you, everything is pretty much a "chemical".

they are fucking with nature. far beyond what they should be.
JWH's compound changes every week to remain legal.
There is a reason natural marijuana works better than marinol. There are 400+ compunds in the marijuana plant working together to balance what it does.

I am not confused in any way, but you sure seem to be.
Argue all you want, ive seen people get fucked up, and not in a good way, on spice, and never on marijuana.

The area of synthetics has been explored, and JWH isnt it.

"Looking at other synthetics they end up being superior to the natural compound that inspired it"
Theres a difference between synthetics you put and cars, and synthetics you put in your body. Synthetic medicine will never be better for you than naturals.
I am not confused at all, although I am struggling to keep this thread on topic. We are talking about K2/Spice and the Synthetic Canabinoids that are used in them.

Marinol is old news and the medical value of that as you say has proven to me marginal at the least.

Marinol's Medical Benefits are not in question here, please refer to the subject of this thread for clarification.
 
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