You have a serious magnesium deficiency, I can see the spots on the leaves, and the red veins can be a sign of phosphorus deficiency.. Water them with epsom salt dissolved at the rate of 1 tbsp per gallon of water. Are you're plants getting calcium, and the rest of the micro nutrients? I'm guessing that you're lower leaves turned color, yet you are feeding them plenty of nitrogen, correct? When I see deficiencies, the 1st thing I check is PH, if that is optimum, I than adjust what ever shortcoming is needed.
What is your feeding schedule, and what are you feeding?