"Indian Pipe" - A unique plant with potential pharmacological and psychological effects

Discussion in 'Hallucinatory Substances' started by cannetix Inc, Oct 17, 2017.

    cannetix Inc

    cannetix Inc Well-Known Member

    This strange looking "mushroom", as many might call it, is actually an exotic type of non-photosynthesizing flowering-plant called Monotropa Uniflora, also known as "Indian pipe" and "ghost plant". Unlike most plants which contain photosynthesizing pigments such as Chlorophylls that generate food (carbohydrates) from H2O, CO2, and Sunlight, Monotropa Uniflora is parasitic, or more specifically, myco-heterotrophic. This means that the ghost plant depends entirely on a parasitic relationship with mycorrhizal fungi, from which it obtains all of its carbon and nutrient supply.

    Although there is very little information pertaining to the chemistry of Monotropa Uniflora in scholarly texts & journals, there are a number of sources that point to its historical use as an opium-substitute that has potent sedative properties, with some even claiming that large doses "can bring deep sleep and ultra-vivid dreams, often bizarre, frequently erotic"


    Some sources suggest that this activity may be due to the presence of high concentrations of salicylic acid, while others suggest that the plant contains small quantities of Andromedotoxin.

    Salicylic Acid is a naturally occurring phenolic acid that results from the metabolism of Salicin. Salicylic acid functions as both a plant hormone (in plant biology) and as the active metabolite of Aspirin (in medicine). Salicylic acid, like most other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) suppress the activity of COX, an enzyme responsible for the production of pro-inflammatory compounds in the body. It is widely understood that COX-2 inhibitors have sedative and analgesic properties, and although Salicylic acid does not directly inhibit COX it is likely that it has some of the same sedative and analgesic properties through pathways that are not entirely understood.


    Andromedotoxin is a Grayanotoxin, which is a group of toxins found in several plant species, but primarily in Rhododendrons. Honey made from grayanotoxin containing plants can cause a very rare poisonous reaction called grayanotoxin poisoning, honey intoxication, or rhododendron poisoning. Honey produced from the nectar of Andromeda polifolia contains high enough levels of grayanotoxin to cause full body paralysis and potentially fatal breathing difficulties due to diaphragm paralysis. Honey containing grayanotoxin known as "deli bal" is still deliberately produced in the Caucasus region of Turkey and sold in 18th century Europe as an intoxicating beverage, according to sources provided on Wikipedia.


    It would be interesting to see some in-depth research done in regards to the potential pharmacokinetics of this widely unknown plant species as well as a real chemical analysis. If anyone knows of any such information please share it here!
    vertnugs and HeatlessBBQ like this.

    HeatlessBBQ Well-Known Member


    HeatlessBBQ Well-Known Member

    @cannetix Inc ... Do YOU have any experiences or leads on this discovery ?

    vertnugs Well-Known Member

    Very cool....nice post.
    cannetix Inc

    cannetix Inc Well-Known Member

    Besides finding it and photographing it quite regularly, and collecting/drying a few samples, no. I don't personally like the idea of taking something when I'm not 100% sure of what it may or may not contain, but I'm sure someone out there has. It also might be worth pointing out that in my experience, if they are not sun-dried they will turn black and liquify much like an "inky cap" mushroom. According to the link below, this suggests that it might contain Hydrolytic enzymes, but that's pretty broad and doesn't tell you much.


    I'm soon planning on grinding up some of the dried samples I have and adding it to a potting mix. Because salicylic acid is a plant hormone that can stimulate rooting it might help determine if this is actually the compound or one of the compounds that are present.

    nobighurry Well-Known Member

    I am a Native American, we have Indian pipe growing along the damp creek all we were told as kids while shroom collecting (morals) is to avoid it or sickness would befall you... Interesting to hear the "sickness" might be of a different variety...
    BlueRidgeGrower likes this.

    BlueRidgeGrower Well-Known Member

    Following in the hopes of an answer....

    HeatlessBBQ Well-Known Member

    What exactly are You searching for?

    Mentally / spiritually speaking . . . .

    BlueRidgeGrower Well-Known Member

    I meant i was following in the hopes someone could come around and confirm effects and such.

    HeatlessBBQ Well-Known Member

    There research behind it is quite scares and unheard of.

    I don't know why One would look into such a thing when You could just smoke a bowl.

    It sounds dangerous and not very safe. So happy trails...

    BlueRidgeGrower Well-Known Member

    I personally am not conducting the research but if anyone has conducted any research id be interested in knowing. And a bowls all fine and dandy but it doesnt scratch that same itch a good ol mindblowing trip does.... at least not for me.

    HeatlessBBQ Well-Known Member

    Then what ever happened to a good ol' mushroom trip? 0_o

    BlueRidgeGrower Well-Known Member

    I tried DMT..... Kinda paled shrooms in comparison. But mushrooms are also super seasonal for me. Only in the springtime to i play with the shrooms

    Z3r0Z3r0 Well-Known Member


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