I have a 2X2X5 box that i built. I also use cfl's for veg and hps for flower. I originally had a 4 inch fan for exhaust as well. However, it got too hot in the box. I was seeing temps in the 90's so I switched to the six inch fan (220 cfm). It dropped the temp but not enough. I found with the cfl i needed to have fans blowing directly on the lights so i got 4 pc fans and placed them around the box. Worked well to keep the temp around 84 but i was nervous for the hps. I bought a 150 W hps that had an option to buy a 4 inch vent flange for the top of the light. I split the 6 inch vent to two 4 inch vents and hooked one to the light and one just to the box. I also took a 80mm pc fan and it fits perfectly in the flange. The other pc fans point up to keep cool fresh air circulating to the top while one vents the light and a small desk fan cools the outside of the light. The other vent is hooked up to the top of the box. The temp in the box is 78-80. To me cfls are harder to keep cool as there is no separation between the light and plant. Its easier to vent an hps.
I tried every way i think i could and found this to be the best. I have avoided active intake because i use light tight air vents.
I think you could do the 250 w hps with the extra foot you have if you can directly vent it. It was a lot of work for me to get this right so i hope this can help.