I've even had bad years where my outdoor plants were half way through flowering and loaded with worms. I had to spray each and every bud until the stuff was running out the bottom but the next day there were dead worms on the outside of probably at least 30% of the buds. You just have to make sure to spray early enough in the day that it will dry off from the outside of the bud so the sun won't burn them and make sure to do it on a day where they will be able to dry out as thoroughly as possible to prevent more problems with mold.