The answer to Agrancan's question will definitely help.
If you absolutely must lose the first facility, it could be worse. If you could keep it, you could probably file for an expansion of facility and then slowly migrate to the new facility and kill the old one off entirely.
If all you have is an LOI from the government letting you start your build, you may have huge issues.
It's a very, very dangerous part of the process to make a change in. I know of an LOI who changed one of their RPIC at this stage and got their application put back in the pile and were told to stop their build. Considering how much of the application is tied to the location, you're in hot hot water.
That said, if you've already established your facility and have it inspected it should be much easier to expand as I noted originally - they have conditions for that in place that shouldn't send you back to the pile in any way.