CBD only

This sounds like a great idea. Coconut oil is already a great food. By using dry ice, there is no activated THC. Do you believe that the THC-A has the same healing qualities as activated THC? Some believe that the CBD only works with equal amounts of activated THC. Others believe that the CBD is what creates the healing properties. This is the first time ive thought about THC-A vs. activated THC.
 
In addition to Rick Simpson Hemp Oil, I also reading about CBD simple and Real Scientific Hemp Oil. These are pure CBD products and won the Medical Cannabis Cup recently for highest CBD numbers. I imagine their availability will take off now that hemp can be grown in the US. But these are in a different category then RSO, which has THC as a primary ingredient.
 

st0wandgrow

Well-Known Member
This sounds like a great idea. Coconut oil is already a great food. By using dry ice, there is no activated THC. Do you believe that the THC-A has the same healing qualities as activated THC? Some believe that the CBD only works with equal amounts of activated THC. Others believe that the CBD is what creates the healing properties. This is the first time ive thought about THC-A vs. activated THC.
I can only base my premise on patient feedback, which has been fantastic when using both high CBD flowers together with high THCA flowers. Again, the full spectrum of canabinoids working synergistically I feel is the best case scenario.

Another point should be mentioned that was brought up in another thread. THCA will begin to convert to THC through oxidization. In other words, the longer you dry/cure your buds the more THC will be present. I try to dry my buds as quickly as possible when they are intended for an oil. If you can't use them right away, it would be a good idea to store them in an air-tight container in the fridge until you're ready to use them.
 

Pangioti

Well-Known Member
This sounds like a great idea. Coconut oil is already a great food. By using dry ice, there is no activated THC. Do you believe that the THC-A has the same healing qualities as activated THC? Some believe that the CBD only works with equal amounts of activated THC. Others believe that the CBD is what creates the healing properties. This is the first time ive thought about THC-A vs. activated THC.
As I understand it, you have to decarb cannabis in order to convert CBD-A to CBD just as you have to decarb to convert THC-A to THC. My dad with ALS responds better to the activated THC more than the THC-A.
 

st0wandgrow

Well-Known Member
As I understand it, you have to decarb cannabis in order to convert CBD-A to CBD just as you have to decarb to convert THC-A to THC. My dad with ALS responds better to the activated THC more than the THC-A.
These are good points and questions. I can only say that the the two patients that I make this for do *not* want to get high when taking this and have both been doing exceptionally well. One patient has dravets syndrome, and prior to taking this oil would have dozens of seizures a day, and is now down to a couple seizures a month and has almost fully removed himself off of all pharmaceutical meds. My other patient has ulcerative colitis and has been taking the oil for about 5 months now. He has dropped his prednisone (steroid) intake from 20mg a day down to 4mg a day and dropping. He was scheduled for a surgery which would have forced him to use a colostomy bag to go to the bathroom in, and the doctors have cancelled the surgery as he is doing so well. It has been life changing for both of them.

Not exactly scientific evidence I'm throwing out there, but it's all I have to go on.
 

potroastV2

Well-Known Member
Well, I can tell you that HempMeds does decarboxylate their hemp extracts, which are mostly CBD, so I guess they think it's a required process.


:mrgreen:
 

st0wandgrow

Well-Known Member
Well, I can tell you that HempMeds does decarboxylate their hemp extracts, which are mostly CBD, so I guess they think it's a required process.


:mrgreen:
I have decarboxylated high CBD cannabis (14% CBD .75% THC) at 300 degrees in an oven for 20 minutes and then put it in a smoothie and drank it ...... and it gets you high. This was about a 1 gram bud. This is fine for people that don't mind catching a buzz, but there are plenty of people who don't want that ie children, elderly people, etc. It works amazingly well without being decarbed. I'd sure like to know the science behind this to find out if the decaroxylization process brings any therapeutic value to the table beyond a no-heat extraction process.
 

potroastV2

Well-Known Member
That's a very similar cannabinoid profile to hemp, and with less than 1 percent THC, I'm surprised that you got any noticeable effect from it.

There is obviously a whole lot that we don't know about the benefits of using cannabis, and especially the other compounds and terpenes, that have neuroprotective qualities or bronchodialator effects and probably many other benefits.


:mrgreen:
 

st0wandgrow

Well-Known Member
That's a very similar cannabinoid profile to hemp, and with less than 1 percent THC, I'm surprised that you got any noticeable effect from it.

There is obviously a whole lot that we don't know about the benefits of using cannabis, and especially the other compounds and terpenes, that have neuroprotective qualities or bronchodialator effects and probably many other benefits.


:mrgreen:
That 14% CBD .75% THC was what the flower tested at. Hemp tests nowhere near that high. A concentrate made from hemp may test at those levels, where as a concentrate from marijuana would tests at 50%-60% CBD. And yes, CBD will give you a buzz once it's decarbed. I didn't believe it until I tried it myself. I was floating on a cloud for 5 or 6 hours after eating that decarbed bud.
 

potroastV2

Well-Known Member
Are you actually saying that a concentrate made from marijuana is somehow different than a concentrate made from hemp?

Both are the same, and you can make your concentration however you want.


:mrgreen:
 

qwizoking

Well-Known Member
i post this alot
For a compound to have "drug likeness" it must have a polar surface area (psa) under 60 angstroms in order to cross the blood brain barrier and reach receptors.. in the polar acid form(thca) has a psa of 66...meaning you will feel effects from cbd as the cb1 receptors give you a high and located in the brain.. the cb2 receptors are located throughout the body and don't require a reduction in polarity..no bb barrier to cross

a psa under 60 is optimum and some will cross up to about 70. thca at 66 will cross in high doses..this would be a huge waste of product however..especially since it takes relatively high doses to get high, after decarbing it drops to 30..
cbda is more polar than thc with a psa of 77 and cbd about 40

you can feel certain effects without decarbing..this is far from ideal

a little science goes a long way.......
 

st0wandgrow

Well-Known Member
Are you actually saying that a concentrate made from marijuana is somehow different than a concentrate made from hemp?

Both are the same, and you can make your concentration however you want.




:mrgreen:
Yes. There are much higher percentages of cannabinoids in marijuana vs hemp.

Do you think that if you took an oz of schwagg brick weed and made BHO out of that, and then took a cannabis cup winning strain with double the percentage of THC and made BHO out of that ..... that the two would be the same?
 

st0wandgrow

Well-Known Member
i post this alot
For a compound to have "drug likeness" it must have a polar surface area (psa) under 60 angstroms in order to cross the blood brain barrier and reach receptors.. in the polar acid form(thca) has a psa of 66...meaning you will feel effects from cbd as the cb1 receptors give you a high and located in the brain.. the cb2 receptors are located throughout the body and don't require a reduction in polarity..no bb barrier to cross

a psa under 60 is optimum and some will cross up to about 70. thca at 66 will cross in high doses..this would be a huge waste of product however..especially since it takes relatively high doses to get high, after decarbing it drops to 30..
cbda is more polar than thc with a psa of 77 and cbd about 40

you can feel certain effects without decarbing..this is far from ideal



a little science goes a long way.......
Very interesting. The only thing I've been basing this off of is patient feedback. I have made oils on the stove top before, and it's night and day compared to a dry ice sift. My patients are getting stoned from the stove top method, and no buzz at all from the dry ice method. Your post confirms what I have believed to be true.
 

potroastV2

Well-Known Member
Yes. There are much higher percentages of cannabinoids in marijuana vs hemp.

Do you think that if you took an oz of schwagg brick weed and made BHO out of that, and then took a cannabis cup winning strain with double the percentage of THC and made BHO out of that ..... that the two would be the same?


I guess you don't understand when I said "you can make your concentration however strong you want it to be." You can continue to say that there is a difference between Cannabis Sativa and Cannabis Sativa if you like, but you're still wrong.


:mrgreen:
 

Pangioti

Well-Known Member
i post this alot
For a compound to have "drug likeness" it must have a polar surface area (psa) under 60 angstroms in order to cross the blood brain barrier and reach receptors.. in the polar acid form(thca) has a psa of 66...meaning you will feel effects from cbd as the cb1 receptors give you a high and located in the brain.. the cb2 receptors are located throughout the body and don't require a reduction in polarity..no bb barrier to cross

a psa under 60 is optimum and some will cross up to about 70. thca at 66 will cross in high doses..this would be a huge waste of product however..especially since it takes relatively high doses to get high, after decarbing it drops to 30..
cbda is more polar than thc with a psa of 77 and cbd about 40

you can feel certain effects without decarbing..this is far from ideal

a little science goes a long way.......

Awesome post - thanks for that!
 

oldschooltofu

Well-Known Member
charlotts web CO (25+:1)
Catatonic WA i think its a 1:1
Pennywise 1:1 about 13% but make sure you test first, some phenos have 0 cbd, as i found out first hand the hard way, kept the wrong pheno.
R4 OR. i just got a cutting of this one 20%CBD 1% THC, cant wait to grow this girl out.

i got 4.5cc of RSO from 2 oz of 1:1 pennywise. gave half of it to 2 cancer patients. yes it was expensive to make, but these peoples health are worth more to me than money, i can cover my costs off flowers, so i donated half my RSO and kept half. but yea at this rate its 40-60$ a cc wholesale is what it cost me to make. thats pretty expensive.
 

OTR99

Member
Are you actually saying that a concentrate made from marijuana is somehow different than a concentrate made from hemp?

Both are the same, and you can make your concentration however you want.


:mrgreen:
ok question. In a column witch is the orange THC or CBD? witch is the red THC or CBD? or better yet witch would fall first THC or CBD I`am running 70-200 mesh. I`am getting good seperation orange always falls first followed a very small yellow band then red mostly well 2 more bands behind that. Sample was decarboxed. Cause I just sampled what I thought was CBD & I`am having a hard time typing this LOL so now I`am all backwards it`s got to be THC that I isolated. "Still Cool!" but if anyone can help ?
 

homebrew420

Well-Known Member
We are currently underway on a reversal of the "our14er" an S1 of the famous R4 from Greenwerks in Denver. Tested @21.39 cbd and 0.91 thc.
S1 and hybrids, both of other medicinal and "drug" varieties will be available in a few months. Our
Tange-istan came in with 4:1 (cant recall actual #s right now) and will be used along with our 1:1 "Dudes Tange".
Fire og and Skywalker will likely be used as well.
come to Boulder CO and we can make it happen.

Peace
 
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