It is possible to test for the presence of LSD in urine, but it is a very difficult and expensive test to run and is very uncommon. Unless there is a particular reason to be looking for it, as in the case of an autopsy...it is extremely unlikely that most people will ever run into this test. It is not one of the SAMHSA-5 standardly tested for in the basic drug test, nor is it included in the extended drug tests. It is not chemically similar to any of the drugs tested for, so should not trigger the tests as another substance.