Pruining/thining during bloom?

Have a question, can you thin or prune a plant during bloom without doing to much damage? Reason not enough grow space for 5 plants,,bottom lateral branching not getting hardly any light, so left on the big fan leaves but cut of 20 lateral gowth(aka really long clones) to thin and open up more room light/air/ ect.. growing 2 DREADY BERRY ..2 short stuff mi5 and 1 free afghan kush ryder,, and as with all reports not sure what makes the kush ryder autoflowering 28 days to sex and 40" tall

I trim all the weak and thin in bloom, just a little at a time.

id go the otther way, super crop them

Why super crop the weak ?

I wouldnt in bloom.. That needs to be taken care of at the end of veg. I try to give my girls nothing but love in bloom, 0 stress