I currently - and have for the last 8 years - grown multiple strains feeding off the same res. I am currently growing ATF, Pineapple xpress, Aff-goo, Super Lemon haze, Pot of Gold and Shiskaberry - all feeding of the same res - running between 750 and 1200 PPM, depending on growth stage. The individual plants assimilate nutrients based on their needs - all I do is give them the choice. I agree that you can tweek 1 strain for optimum out come, but the variety more than makes up for the slight decrease in overall production