Humidity can be tricky to accurately control considering healthy plants are natural humidifiers. To give helpful advice, one would need to know more information such as the layout of your grow room. Where is grow room located, as in stand alone or inside another structure? What climate is your area, desert, tropical or...? How big is the grow space? How many plants and at what stage? What method of growing are you using?
Yeah lots of questions but not easy to constructively comment on the unknown.
Can you put the dehumidifier outside the grow space so defrosting operations do not effect it?