Do you have any pictures? That would help a lot. Whats your grow medium? What kind of light and wattage do you have? What is the temperature? How old are your plants, are they in veg or flower? When you start using Big Bloom depends on you. I have read though that its best to start introducing it to the plant when it shows its first preflowers. So based off what you said, I would use maybe a quarter strength dose next time you feed, but before you do that we need to figure out if your plants are suffering from nutrient burn or some other problem and the only way we can get a good idea to help you further is if you provide us with pictures and answers to the questions I asked.
We'll go from there
Edit to add this: Whether or not this affects your yield depends on a lot of factors. So the more info you give us the better we can get that answered for you.