Natural resistance to Diphenhydramine HCL?

I've experimented several times with diphenhydramine and haven't gotten any real good results. I've read that many people get great results with 350mg, and I've taken 650mg after being clean for a month and haven't seen anything weird. The best is some slight movements of objects on my peripherals. The only time I saw something was with 950mg, when I saw my sister and my niece sitting on the kitchen sink. They were gone a few seconds later, and that's the best I've seen. BTW, I weight 94kg and I'm 1.92m tall. Is it the size?

First, with benadryl (short name ) "good results" are subjective in my opinion. Commonly, people just get really lethargic and go to sleep. Not everyone talks to a pair of jeans, or dreams with their eyes open. Secondly, tolerance for this stuff can rocket up pretty quickly. Repeated dosing might just compound the problem.

Also, although hallucinations or "dreaming with eyes open" can happen, it will be very brief and often lasts only a few seconds before one snaps out of it. It is common to see people if one hallucinates at all. Personal note: ugh, otc pill based delirium

That being said, did you get sleepy at all when dosed 650? Did you dose that 650 all at once? Are you on any other medications / drugs?

Your size might be part of it, and it is possible you have a high natural tolerance.

Benadryl isn't like a psychedelic acid trip.

I think I fell asleep and started dreaming for a few minutes and then woke up again, many times during the whole experience. I was actually looking for that scary experience that everyone talks about. I'd consider it "good", having never experienced anything other than a high. I didn't get the feeling that I was sleepy, though. It was hard to think so maybe I didn't notice. At it's peak I'd forget where my bed was even though it was behind me. I don't take any other medicines.

I noticed the quick tolerance. A few days after the 950mg I tried it again and didn't get any satisfactory results. I was blinded for half of the next day, though. I couldn't read anything that was at arm's length or closer.

I know that it's lame with OTC but getting acid or shrooms is very hard where I live.
I've also taken DXM and apart from the drunk feeling I haven't felt anything else (~350mg)

Your experience sounds like an average time with benadryl, honestly. Between a friend and I, I think we did this stuff enough out of sheer boredom and there was only a couple times a piece where we saw someone that wasn't there (eg. i thought a pair of jeans was someone for 5 secs). Difficulty thinking and holding a train of thought are more common imo than any of the hallucinatory stuff.

I guess one last thought, Did you take the diphen on an empty or a full stomach, or like 1/2 full? I think that stuff kicks harder on an empty stomach.

Although, I must admit that you've experience most of what diphen has to offer. You could stop now and not miss anything great. Hell, to this day I can't take that stuff anymore to sleep or ward off allergies; after taking so much over a period of time my body reacts differently to it now and I get jittery.

Quit while you're ahead Benadryl sucks and fucks up your eyes in higher dosages..

Well, I think I'll stop using it by itself. When I started smoking weed for the first time in over two years, I took two 25mg pills of diph and I got some amazing closed eye visuals. It seemed like my subconscious mind was playing in its own playground. Have any of you combined low doses of diphenhydramine with high doses of weed?

OneGoodUser said:

Well, I think I'll stop using it by itself. When I started smoking weed for the first time in over two years, I took two 25mg pills of diph and I got some amazing closed eye visuals. It seemed like my subconscious mind was playing in its own playground. Have any of you combined low doses of diphenhydramine with high doses of weed?

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I've combined 80mg of ritalin with 100mg of diphenhydramine, just trying to get to sleep from the ritalin at around 4 am and didn't get to sleep until 8am. Everytime I was about to fall asleep I got this weird spaced out feeling in my head and think I was dying in my sleep and wake up... this went on a few times through out the night. One of which included me throwing the sheets off my bed and seeing my feet 5x bigger then they were like they were clown shoes for 5-10 seconds then I rubbed my eyes and they were normal size again. After that I gave up and stayed up as late as I possible could until I passed out. Not a healthy or fun experience to say the least, I wouldn't recommend mixing diphenhydramine with anything it's a strange enough drug by itself.