A good soak in vinegar every once in awhile works pretty good. Are you planning on running short bursts or long? Obviously the longer the time frame the nozzles are delivering, the more build-up they're going to incur. You're veg time & nute choice/concentration will play a big role. A little aero system is just the thing for figuring out these sorts of details. Slap it together & give it a go. You'll learn a bunch along the way.
We have been using a Sentinel DRT-1 set for between 1-3 seconds depending on stage of growth. We just purchased the Multiponics timer which operates in fractions of a second. There's not a lot of choices unless you DIY.