IBL, negative effects?

Hey so when you look at certain breeds of dogs, wolfs and cheetahs in general you see that their genetic diversity has been fucked either through human breeding or a bottleneck in genetic diversity at some point.

Obviously inbreeding and IBL can create a stable phenotype but wont it lead to negative detrimental traits as well? Do breeders routinely breed IBL with similar strains in order to refresh the genes?

Just curious

not that i've seen. regarding sativa dominant IBLs... almost every time i see them, they're polluted with indicas instead of trying to get "hybrid vigor" out of strains most like them. i REALLY wish world of seeds chose something like burmese or even cinderella 99 to cross with their columbian gold instead of some stony indica that only drags yet another superior strain down to the hash smoking cesspool that is 99% of the total market.

in my experience, breeders chose opposites instead of similar gear and especially nowadays use hybrids instead of IBLs like those used in the first indoor strains. i doubt many breeders use afghani for anything but indica dominant strains and instead use stuff like NL#5 & white widow

lack of variation. this can be detrimental to the species but i dont think it has an outright negative effect, some mutations occur (sometimes harmful) in inbred strains that are less likely to appear in f1's

A short answer to your question is the only negative effects you are going to see are the ones you choose from your breeding pairs. I mean when you choose your breeding pair you are going to incur whatever bad traits they have either shown or recessive. Those are going to be expressed somewhere down the line given enough generations and the method you use to select future mates.
IMHO cubing is the fastest way to stabilize a strain but hardly the best. Today everyone wants the fastest results possible but by doing this you are certainly locking up your genepool. I guess you could say this is what people have done to dogs with these pure interbred muts, good shorterm results but not good down the line.