For sure - I saw a thing on the news today just talking about how much BPA you get in your system solely from eating food from a can. If you smoke you're already putting smoke in your lungs -- the great thing is cannabis smoke actually FIGHTS lung tumors and probably brain tumors as well -- but who knows what else you're getting if you're not going organic.
God thats crazy man,yeah everytime you turn around anymore theres another study out about what else is killing you on the daily lol.
You can get by without supersoil. When I last grew I basically used a watered down super soil that had some guanos and amendments in it but not as much as supersoil. I used regular organic nutes (pure blend, fox farm big bloom, etc) and got good results with that too. It is just going to be a bit harder than super soil because you're going to have to keep a bit more of an eye on your plant for deficiencies. Even if you're still using bottled nutes, I highly recommend feeding with a steeped organic tea that's been bubbling for a day or two every other feeding. You can pretty much use a gentle organic tea every time you water.
The problem you will almost certainly run into that I had is rapid yellowing of the fan leaves in flower due to not enough N. Some people don't see this as a problem, most organic growers do

You'll need to supplement with some guano teas that have decent N in relationship to the P or fish emulsion.