Its the amount of nutrients that you need to put in the water/solution to raise the ppm 250 ppm higher then what it originally is.
Example: If your tap water has a PPM of 100 then you would add that nutrient (the one that says to start at 250 ppm) till your PPM reader reads 350 ppm
You would need a PPM meter to make sure you use the right amount unless if has different directions, maybe look online for a per gallon recipe. What nute is it?