what i mean is that people have been experimenting with natural substances for thousands of years (shamanic use) - and my attitude towards drugs is if it is natural i am happy to take it.
if it is synthetised by some bloke in his garage or worst by money grabbing bastards in some shady laboratory i don't trust it. simple.
if we could only have more legal substances available from known and trusted sources then my attitude would be quite different.
regardless of where you buy it - street dealer or some website you cant be really sure what is actually in it - where as with plants you grow yourself it is a different story.
that is my point of view - i know lot of people will disagree...
i am occasionally using some powders myself (very occasionally - used to a lot more in the past) BUT MY RECCOMENDATION IS STICK TO WHAT MOTHER NATURE GAVE US.
peace