Sure! You need lights, and fans. And I read you can start 12/12 light cycle at the time when the plant is a 1/3 of the overall height you want it. I wanted mine about 3' +/- so I switched to 12/12 at about 12". They are now 16 days into flower and 25" so, I'd sday that is working about right. There is a lot of other good info on here. But YES, you can grow all weed inside if you can create the right environment