Detection in biological fluids
JWH-018 usage is not detectable with the usual immunoassay screening methods employed for detecting cannabis use from urine specimens. Determination of the parent drug in serum or its
metabolites in urine has been accomplished by
GC-MS or
LC-MS. Serum JWH-018 concentrations are generally in the 1-10 μg/L range during the first few hours after recreational usage. The major urinary metabolite is a compound that is monohydroxylated on the alkyl side chain. This metabolite has apparently not yet been quantitated in urine.Detection in biological fluids
JWH-018 usage is not detectable with the usual immunoassay screening methods employed for detecting cannabis use from urine specimens. Determination of the parent drug in serum or its
metabolites in urine has been accomplished by
GC-MS or
LC-MS. Serum JWH-018 concentrations are generally in the 1-10 μg/L range during the first few hours after recreational usage. The major urinary metabolite is a compound that is monohydroxylated on the alkyl side chain. This metabolite has apparently not yet been quantitated in urine.