Shredder111.... When you mix up a batch of soil - from bags, wet it, let it sit overnight - then it is ready for use. As long as, you don't buy super cheap, low quality soil / soil amendments - you should not have any problems with pest or weeds. The cheap stuff is no name Dollar Store or Walmart stuff. The Good Stuff is (brandname or product name) : Black Gold, Promix, Happy Frog, Ocean Forrest, Coir 1 Coco, Light Warrior...etc...
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If you are mixing up Super Soil - soil with all the fertilizers your plant will use for the entire grow - at one time. It requires one month to cure (evenly distribute the NPK throughout the whole mix). The receipe for Super Soil in in Subcool's Organic Sub-forum.
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Hope this helps...
Keep it Real...Organic....