I thought the average BTU recommendations are 4000-4500 BTU's per 1000 watts of light. Therefore, if I were using 4-600 watts of HPS, that's 2400 watt's total. So, if you do the math, 12000 BTUS of a mini split A/C would do the trick, right? 22,000 BTU's sounds crazy. Please correct me if I'm wrong!IdealAir minisplit calculator says you need 22000 btu's to cool that room. you could fit 2 3'x6' trays or 4 3'x3's. you could also do 2 1000w on light movers. If running 4 600, get a 4 light master control and run 220v from that to your panel off a 30 amp breaker or run a subpanel to your room.
My room is only sealed when the lights are on. The plants use O2 at night and CO2 during the day. Also keeps the smell down, otherwise you need a scrubber in the room. I use the IdealAir 70 pint dehumidifier and a 12000btu minisplit in a 5x9x9 room.