Can i spray for Worms/Catipillers while plants are fully budding ?

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View attachment 1146590IMG_1069.JPGIMG_1071.JPGIMG_1072.JPGI went to look at my Girls the other day only to find a dead spot on a main bud :cry: upon further looking i found what seems to be worms. Since their in full bloom(plants) can i still spray these or is picking them off my only option. This is my first year trying out door and in a total panic about these dam things.. any help is greatly appreciated
 
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