These have all been spray multiple times over the last 6 weeks, starting before they had spots. I did 2 sulfur sprays , without copper, and 2 of Cease, a biological fungicide that contains bacillus subtillus. Fall is fairly dry here, septoria usually backs off until you are trying to finish up flowering. Then, as the plant gets old and weak, it attacks the sugar leaves, and then you are done. The weed is still pretty good, even when it doesn't look like it! Not as good as it can be. INsanely wet spring! I do have a very resistant plant which I will breed with for next year. This came up in late March. The close up shot shows where it is touching another plant that has septoria.