It has come to my attention that the legal high known as Spice contains the synthetic cannaboid JHW-018 among other cannaboids. If these cannaboids attach themselves to the same receptors that weed does, is it possible that they could wear them out or even damage them permanently? After all...
This doesn't apply to everyone. But I've heard a lot from people about how they can not get as high as their first time. Is there a reason for this? Is it just a matter of tolerance that needs to go down? Or is it just impossible?