How much MAM-2201 to herb ratio?

How's this for irony... Heroin has been around and in use for well over a century; morphine and related compounds (i.e. raw opium) for much much longer. Heroin\morphine have been used extensively and researched quite extensively within the medical\scientific community for the past several decades such that we know how such compounds work and what kind of effects present with short-term\long-term usage. We know that morphine and related compounds are psychologically and physically addictive (stopping abruptly after prolonged use results in a physical withdrawal syndrome). We know morphine is a depressant; it slows breathing and heart rate and can do so to the point of death at high doses and in less tolerant individuals. We know morphine will cause your pupils to constrict, it also causes constipation which can be severe. Morphine in particular may also possess some degree of hepatic and renal toxicity if used long-term, perhaps more-so in those who already have liver\kidney disease. And we also know what morphine\heroin do not typically do... such as cause brain damage, damage to the heart, or any other major organ (this is one reason why it is so frequently used in medicine).

These research chemicals, on the other hand, have not seen such wide-spread use (not even in lab animals!). Some of these chemicals may have been first administered to humans less than a decade ago. Their long term effects, especially with frequent use, are entirely unknown!

Yes, but here is something to think about. Morphine is isolated out of opium. Then is engineered to make heroin. Morphine and heroins long term, and short term effects are quite similar. Yet heroin is so much more illegal because since it comprises of more components, there are generally more side effects. Also they used to use heroin as a pain medicine and cough syrup until morphine was made.

Now these research chemicals are not to shy of original drugs. They are analogues. Mescaline is a phenthylamine, mushrooms are tryptamines(DMT). Most RC's mimic their chemical structure and produce similar effects. It would make a lot more sense if the long term and short term effects are at least similar to that of their illegal drugs. Of course some of that would also have to do with HOW similar they are.

I doubt this goes for the cannabinoids(well not cannabinoids anymore, the AM/MAM compounds are tryptamines). At first it did. I doubt jwh 018 is near as harmful as AM 2201. JWH is more subtle, like marijuana. Now AM/MAM or some of the newer ones will rip your mind to shreds.
I think the health of these is more determined by the indivisual. Ive read things about people using synthetics for years and they are fine. I used synthetic marijuana for the longest time. I recently kicked the habit so this thread is obsolete unless you yourself want to learn how.

In that case its all in the thread your a thousand-aire.

Originally Posted by high|hgih

Yes, but here is something to think about. Morphine is isolated out of opium. Then is engineered to make heroin. Morphine and heroins long term, and short term effects are quite similar. Yet heroin is so much more illegal because since it comprises of more components, there are generally more side effects. Also they used to use heroin as a pain medicine and cough syrup until morphine was made.

Now these research chemicals are not to shy of original drugs. They are analogues. Mescaline is a phenethylamine, mushrooms are tryptamines(DMT). Most RC's mimic their chemical structure and produce similar effects. It would make a lot more sense if the long term and short term effects are at least similar to that of their illegal drugs. Of course some of that would also have to do with HOW similar they are.

I doubt this goes for the cannabinoids(well not cannabinoids anymore, the AM/MAM compounds are tryptamines). At first it did. I doubt jwh 018 is near as harmful as AM 2201. JWH is more subtle, like marijuana. Now AM/MAM or some of the newer ones will rip your mind to shreds.
I think the health of these is more determined by the indivisual. Ive read things about people using synthetics for years and they are fine. I used synthetic marijuana for the longest time. I recently kicked the habit so this thread is obsolete unless you yourself want to learn how.

In that case its all in the thread your a thousand-aire.

Two instances of dissent:

The bolded is incorrect. Heroin is a single-component drug as is morphine. Its regulation has to do with its very fast effect when injected or smoked.

Also MAM-2201 is not a tryptamine, but a 3-alpha-napthoylindole. cn

Morphine effects are very fast when injected, Ive never smoked morphine so I don't know about that..
Why would it make morphine so much more used? I bet 99% pure heroin would be much much more prevalent at killing pain. I know for a fact some high quality dope will have you more painless than a rock.

Same goes for morphine really though...

But hmm, I read somewhere that AM 2201 was a tryptamine I guess thats wrong too? Then I was just assuming that MAM would be one as well. I mean all it has is an added methyl ring

Heroin is diacetyl-morphine... it is merely a molecule of heroin with the addition of two acetyl groups. The acetyl groups increase is permeability through the blood brain barrier, but once inside the brain heroin breaks down rapidly into morphine (after 6-monoacetyl-morphine). Experiments with ex-addicts have supposedly shown that there is no subjective difference between heroin and morphine when equipotent doses are injected. I tend to disagree, as personally whenever I've injected morphine (from tablets) I seem to experience a greater histamine release, pins and needles in the spine and neck which at the very least distracts from the enjoyment of the rush.

When I used to make it, I would get almost 2 ounces of plant material for every 1 gram JWH-081. It was pretty strong stuff, too. I'm not sure how potent MAM-2201 is as I quit spice a while ago... but I assume it's the same process with acetone and a spray bottle pretty much. 2 ounces per gram is the same as 20mg/gram... which is not gonna freak out newbs, but it's still decently strong.

it's good money.

Damn! MAM 2201 is VERY potent. As far as it compares to JWH, I think its much much more... Fun jwh can have the same effect though with higher dosages. AM, and MAM are just incredibly strong.

I might have said this in this thread already but a friend of mine made his with AM 2201, and some JWH compound all put into one spice. We were smoking it one time and my other buddy wanted to try some. He was told no because he'll freak out and could die since he'd never smoked spice before. Well guess what? He smoked it anyways, surprised he didnt have a fuckin heart attack he looked pretty gross.. But he was fine like an hour and a half later

wait, so you're unable to grow good pot yourself so your next best idea is to concoct some home made smokers choice pack? After a week of you making this "bank", they will realize their money is better spent on mexibrickweed.