I'm too stoned to give this thread the proper introduction it deserves, but no matter, this thread is about an over-the-counter heartburn medication called Tagamet. The actual drug is cimetidine. Anyway, supposedly if you take a dose of this medication (recommendation that I've heard is 800 mg or 4 pills) about 45 minutes to an hour before you smoke, you will get super baked for longer than usual off a small amount of bud.

I'm too high to remember exactly how or to even bother checking another internet source, but Tagamet basically prevents cannabinoids from being filtered through your liver for a few hours, or something very similar to that. So...you smoke and get a large buildup of THC and other cannabinoids and they stay floating in your body for like 3 or 4 hours instead of being normally filtered out. It's doesn't 100% block the filtering, but it blocks it quite a bit.

One of my very experienced psychedelic-using friends recently tried taking 4 Tagamet before a toke (this guy has a high tolerance and needs 2 bowls of good chron to get high) and said that he was stoned stupid for 5 hours off 3 hits. I don't know if that's a realistic expectation, but I've heard multiple accounts of Tagamet being used to increase and lengthen a weed high, and I plan on trying it soon.

Perhaps someone here has some experience? Or maybe someone else can properly explain how this works?

and if you take oxycontin and weed you get HELLLLLAAA HIGHHH

the point of this thread?

No, the point is that this pill gets you higher from the weed itself by preventing a lot of cannabinoids from being filtered out of your body. It just keeps the THC in your body longer when you smoke. Or at least that's how I understand it. It has nothing to do with getting high from the pill; the pill itself, even if you took a handful, would only make you slightly dizzy at worst. The pill acts with the weed to get you higher. Synergy. Doesn't that interest anyone else?

keeps the thc in your system longer and prevents it from being filtered as quickly? That doesnt necessarily sound like a good thing, especially if you have to piss clean

is this real

well imObama, I suppose you wouldn't consider an attempt at this method then...

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idk ive never heard of it

Hate the site and hate to post a link to it, but...

Holy shit! Tagamet HB extends and improves a weed high! - Community

Thread at Totse explains how this works and whatnot. Tons of testimonials in there. This is definitely for real and I plan to try it fairly soon.

as of January 1st, i have a country to run!

please explain how a heartburn pill makes a weed high last longer? the only way i can think of is if thc and tagamet are metabolized by the same enzyme.

i just read the article and i was right. they are both metabolized by the same enzyme (CYP2C9). this may actually work as when things compete for enzymes their effects can add up.

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