Mental91
Active Member
So here it is people! I gave a chemist 500 bucks to find this for me and he did. It's extremely easy! Good luck getting chems to make it though. Remember you heard it from me first!
So, in a dry flask 6A, equipped with a reflux condenser are placed 20 g of sodium hydride, poured 100 ml of dry DMSO, stirred, added in small portions (5-10g, and the mixture is heating, cooling should be good) 100g 1-nafindola periodically stirred at room temperature, 30 min. Then add 77g of n-pentilbromida (amyl methyl). The reaction mixture was incubated at 65 gr. Celsius 3 h on an electric hot plate with periodic stirring. PRODUCT fall as oil! The reaction mixture was washed 3 times with water in 5-fold volume.
Attention! Sodium hydride ignites on contact with water! Be careful when working with him!
Solvents:
The product is highly soluble at 35 grams. C in diethyl ether and isopropyl alcohol, worse than in ethanol.
Do a better job with the ether, maybe, he flies at room temperature and the basis for faster drying!
The water insoluble product!
Applied in concentrations from 0,5 to 2g per 10 g basis, depending on the desired effect.
** How to wash?
To wash pour into a beaker (1L) 200ml oil and add water, mix thoroughly and allow the oil to settle, then drain. Repeat 5 times until the water is clear.
** For those who do not want to bother with flushing questions
The reaction mixture was flooded with water at 5 times the volume and mix, then poured 200 ml of ether, stirred and made to stand. The reaction mixture was divided into 2 layers (high - oil in the air, the bottom - the water with impurities). Collected the top layer. If necessary (if the previous operation to select all the oil could not) add another 200 ml ether, stirred and give stand, then collected and combined with previously collected. All product is ready for further action!
So, in a dry flask 6A, equipped with a reflux condenser are placed 20 g of sodium hydride, poured 100 ml of dry DMSO, stirred, added in small portions (5-10g, and the mixture is heating, cooling should be good) 100g 1-nafindola periodically stirred at room temperature, 30 min. Then add 77g of n-pentilbromida (amyl methyl). The reaction mixture was incubated at 65 gr. Celsius 3 h on an electric hot plate with periodic stirring. PRODUCT fall as oil! The reaction mixture was washed 3 times with water in 5-fold volume.
Attention! Sodium hydride ignites on contact with water! Be careful when working with him!
Solvents:
The product is highly soluble at 35 grams. C in diethyl ether and isopropyl alcohol, worse than in ethanol.
Do a better job with the ether, maybe, he flies at room temperature and the basis for faster drying!
The water insoluble product!
Applied in concentrations from 0,5 to 2g per 10 g basis, depending on the desired effect.
** How to wash?
To wash pour into a beaker (1L) 200ml oil and add water, mix thoroughly and allow the oil to settle, then drain. Repeat 5 times until the water is clear.
** For those who do not want to bother with flushing questions
The reaction mixture was flooded with water at 5 times the volume and mix, then poured 200 ml of ether, stirred and made to stand. The reaction mixture was divided into 2 layers (high - oil in the air, the bottom - the water with impurities). Collected the top layer. If necessary (if the previous operation to select all the oil could not) add another 200 ml ether, stirred and give stand, then collected and combined with previously collected. All product is ready for further action!
