You can't have a true aero system sit for 12 hours with no misting. Your roots will dry out. You will need at least 1-2 mists throughout the night.
I've heard that intermittent misting can increase results. I think that this has mainly to do with res temp increase from the pump running 24/7, therefor decreasing DO and risking infection. IMO, if you are using a chiller, you can just run 24/7, though. Once your plants have good roots established, the mister gives plenty of constant o2. They do not need a "drying out" time in an aero system.