Cannabis Receptors and Cannabis Tolerance Breaks

I believe there is a debate of cannabis not building a tolerance in the cannabis receptors and no need for breaks using them to increase the receptors response, only switch strains to entice the cannabis receptors again.


I flatly believe in breaks to increase the response, from 3 days to 6 weeks and that 60-70% leaves your body the first week and the last 30% in the fat cells that takes the rest of the 6 week maximum for a complete cleansing of any remaining residues of cannabis.

So, if I have the discipline to abstain for the maximum time can I conclude that my Cannabis Receptors will have maximum response and slowly drop off once again?

I think a break makes a difference

switch it up sativa - indica. you can always take a break from smoking at work LOL

i think a break is insane-
i do SLOW down once in awhile, and that does make a difference (at the moment i have only 2 strains)
but i also notice that my tolerance concerning opiates is much different, it's high from the get and take 1 pill every 6 hours for pain gets old quick, in 3 days of constant use i'm a 3X dose

When I give a break. I give 2 months break minimum(when tolerance is maximum and nothing happens) and after that break i always smoke stuff that friends say it does nothing, and get stoned. You can try this on any strain of cannabis and see what I said. Of course it's true that if you smoke a strain for a week than switch it to a noticeably different but a little weaker strain, you'll get higher than the last day of the first strain.

I think there may be some truth to the idea that tolerance is built to a strain more than marijuana itself. For months I was vaping .2gs in one sitting each night with my Iolite portable vaporizer. I took a month long break and my first try with it afterwords (same exact stuff from the same plant) it didn't feel any stronger than I remember it. This led me to believe that either my tolerance is very strain dependent, or that my brain recovers from the tolerance of at least .2g in a 24 hour break period (and that taking any tolerance break was a waste).

I've read that the byproducts of using marijuana that get stored in fat cells and cause people to fail drug tests has no effect on tolerance and cannot be exercised out to get high off of because they are broken down byproducts.

I wish there was more research into the subject of marijuana tolerance and not just the effects of using marijuana. Does anyone have any links to research performed on tolerance breaks and switching strains?

Breaks definitely help my tolerance, but I often just use more or switch to a higher strength product. Well, until that doesn't work either... then it there is little choice but to take a break.

Yes we can build a tolerance to cannabis but not as much as coffee. I for one use about 20 grams a day for pain control and my first joint of the day is about 1.2 grams... I can smoke 2 or 3 in 1 hr and the high is the same as when I smoked my first. I change my strain depending on my day, more sativa in the morning uplifting , 50/50 strains in the afternoon help me and heavy indicas for night for sleep . I can not takes breaks for it cause me pain. I choose to change my medication through out the day to help me with tolerance. I also take Canna Caps 80ml 2 times a day and few baked goods. My receptors are always firing..

I have found as a medical user that since I am a daily user that sometimes a change of strain is required... sometimes just a 3 day hiatus on a different strain is a good thing... I also use different strains at different points in my day.... Citrus orange sativaindica hybrid during the day, Trainwreck to finish the evening, White Russian to go to sleep with.... have some Kush, G13, and 13 Dawgs to mix it up...

strongest high i ever had was about a month ago, i had abstained for only 6 days and i switched strains, my head spinned like never before and i ended up throwing up! it was too intense more than i really wanted lol

jdizzle22 said:

I think there may be some truth to the idea that tolerance is built to a strain more than marijuana itself. For months I was vaping .2gs in one sitting each night with my Iolite portable vaporizer. I took a month long break and my first try with it afterwords (same exact stuff from the same plant) it didn't feel any stronger than I remember it. This led me to believe that either my tolerance is very strain dependent, or that my brain recovers from the tolerance of at least .2g in a 24 hour break period (and that taking any tolerance break was a waste).

Click to expand...

It was completely different for me. I have to say, at times when I smoke a lot, I smoke way more than people i smoke with. When smoking, I mean "a lot" of smoking. Sometimes it's like 10 times, or twenty. Rarely(this has happened 2 or 3 times with experienced smokers-i'll tell this-) they sleep, and I wake them up in the morning still smoking. Here, I didn't mean what you may think of. I just want to tell something. Smoking much is not an advantage. The advantage is smoking less. As I stated before, If you smoke less you get higher. After I figured this I mostly smoked less. But sometimes you get carried away and don't notice it.

I'm sure of body tolerance vs. strain tolerance. I wish I had the chance to test this in a laboratory and have scientific results. There is also a strain tolerance as you said. But this is far less than body tolerance. And I've heard 24(48 and so on ) hours is enough to set the tolerance. But I can only say it works vice versa on me. The body tolerance can be also called mind tolerance because it's mostly psychological, but it's the plant which gives that psychological effect. For example. I and my friend were on vacation and we had 1 week ahead of us before we return and we had only about 5 grams of weed. And that weed was a weed put in a car engine for safety on transportation(!). Dealer said it's a little brown because of engine heat(!). It was shit man. Really shit. Did nothing without alcohol. But after four days, we only had one joint left. And we didn't even get stoned with that stuff before(We were smoking at a mid-high stage at that time.) We saved the last joint for the time that it'll be needed most. That time was the 6th day and we got stoned for only smoking a joint. That day i realised that what weed does to people is psychological. I've seen people acting like they overdosed on something seeing hallucinations, puking etc just after 2-3 puffs. I think the head is psychological. What you feel is psychological. So everything is...

I remember after quitting 4 days and smoking a joint, and feeling nothing. If it was about strains, it was different and good as my friend said but i felt nothing(a breakdown period is needed if you smoke "a lot"). But after two months I've smoked a joint with the same friend and got really stoned and before that he said it's not that good. This is a question that really needs the support of science. I have much to tell. But this is a hard subject. It's damn hard to tell what i think in English, I wish I could have told these in my mother-tongue language. And hope you understand what I told.

I can say things about John Berfelo said because of the people I've seen but it may cause people to think negatively of marijuana If you know what I mean.

i believe tolerance has to do with a specific strain rather than all mj period.

t-breaks don't do anything for me...except make me irritated!

It's not so much a specific strain as it is indica dominant versus sativa dominant. It also has to do with how far along in flower the mj was harvested, for me I can smoked indicas until I have to smoke grams to just get high and then switch to sativa and its like I'm about half the tolerance I have for indicas. Also, everyone gets fucking stoned on resin, that shits magic I don't think you can build immunity to that.

ExDex1x1 said:

It's not so much a specific strain as it is indica dominant versus sativa dominant. It also has to do with how far along in flower the mj was harvested, for me I can smoked indicas until I have to smoke grams to just get high and then switch to sativa and its like I'm about half the tolerance I have for indicas. Also, everyone gets fucking stoned on resin, that shits magic I don't think you can build immunity to that.

Click to expand...

exactly. if you think you have high tolerance smoke a gram of hash and tell me you're not high lmao

All you guys really need is just one magic word:EXERCISE!! I, like many on this post, use to smoke too much for my personal liking.Im from deep texas so for years i would go through about a half ounce of schwag a week.then i moved where KB was available and then it was about a half ounce of that a month. For some i know thats moderate but it was interfering with my daily life and i decided to take a break. The first few days were strenuous ofcourse but then i started developing a work out regimen. I started doing push ups,sit ups and crunches every morning before work and i would go hiking or rock climbing most evenings and weekends. i even started eating healthier. i went on like this for about a month and i must say it was wonderful.it made me wake up and realize that id been doing way too much of a good thing. unlike a few others on this forum i still missed it though.i decided to see how i felt only smoking every 3 days and still keeping my hobbies and eating well and it feels like the first time everytime i smoke. exercise/nutrition boosts your seritonin levels and makes getting high feel amazing!! then again i prefer to be an active person and i realize everyone has their preference and needs, especially medical patients. nevertheless my tbreak taught me that i had to limit myself and stay active to really enjoy the benefits of getting high and in my opinion, how well you manage yourself has as much to do with it as how long you take a tolerance break.

here is the Truth. Basically your brain regulates tolerance and not the drug (most drugs wear down your brain and take more to be as effective, marijuana works differently), and the only way to make tolerance go down is to abstain long enough for receptors to grow back or stick their private parts out in the open again

http://www.marijuanalibrary.org/brain2.html