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  #11    
Old 12-06-2008, 08:29 AM
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This tends to get asked alot.
I would: stop smoking dope now, exercise a lot (aerobic), drink as much water as you can stand. THC is lipid soluble so if you have lots of lipids in your body (if your fat) you will have more stored THC. This can be thought of as the drugs volume of distribution or Vd. Think of it this way, if you are super skinny with no fat no matter how much you smoke your Vd is like a dixie cup but if you are fat as you continue to smoke you store THC so your Vd is like a 5 gallon bucket. The bigger the Vd the longer to cleanse. If you drink lots of water your body will cycle the metabolites and waste in your blood out via renal elimination at a somewhat higher rate and allow you to more rapidly (within reason) eliminate stored THC from your Vd as your lipid stores of THC attempt to maintain equilibrium with the THC in your blood. This is called first order kinetics (zero order kinetics is a steady state of elimination regardless of other variables). Making your body metabolize stroed fat from exercise and drinking a lot of water will optimize excretion of stored THC. Somone mentioned cranberry jusice to change blood ph, that won't work. Your body is smarter than you and has lots of mechanisms to buffer blood ph so it really stays in the same range. Someone else mentioned taking creatine to promote increased creatinine in urine. Creatine is a high energy substance utilzed by skeletal muscle mostly as an intermediate to sustain exercise for about 1.5 minutes when you have exceeded your aerobic capcity but not enough that you are in a fully anaerobic mode, the result of creatine metabolism is a waste product called creatinine. The kidneys excrete this in a relativley constant amount so it is a useful clinical tool to determine kidney function. Decreased urine creatinine coupled with increased blood creatinine likely means renal (kidney) problems. This is referred to as glomerular filtration rate or GFR. Drug tests that assess urine levels of creatinine use this to determine if the urine is diluted. Urine creatinine should stay near normal even if you ingest a lot of water because GFR is relatively fixed, however if you dilute your urine with water or take a diuretic it will lower your urine creatinine and cause your test to be considered a failure. The only way to truly increase urine creatinine is to increase GFR (not feasible) so taking supplemental creatine does not necessarly equate to higher urine creatinine. Go to a doc-in-box place and pay to have your urine tested for marijuana metabolites. These places use advanced lab equipment that can assess to a level of 10 ng/ml which is what an employer will do whereas home tests have a cutoff of 50 ng/ml so you could test negative at home but positive on an employer test. Hope this helps.
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  #12    
Old 12-06-2008, 12:55 PM
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bradlyallen2, first and foremost +rep, sorry about the comment I was going to say good responce on the Best way to clean out thread, but I accidentally hit enter early! The only thing that I wanted to pick out is the cranberry juice one, it's actually pretty common that people use acidic compounds like cranberry juice or some people even nasty vinegar to lower the half lives of drugs like amphetamines (which are heavily destroyed by an acidic environment), so using an acidic product will lower your body's PH level and will destroy the metabolites that are sensative to an acidic environment.

I wasn't sure about the creatine matter, but I figured that atleast trying to replinish creatine into your body and muscles could atleast help you maintain somewhat normal creatine level (I'd still try it for the hell of it, as I have it in my cabinet by the fucking crate lol).

But great responce and thanks for the info man!
peace
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  #13    
Old 12-06-2008, 01:19 PM
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I stand corrected on the cranberry juice, I did some googeling (I like to use the google when I'm on the internets , it's a series of tubes. ) and cranberry juice allegedly acidifies the urine. What are the implications of this? For THC I don't know. It is common practice to change the ph of urine with substances (typically given intravenously) such as NaHCO3 (sodium bicarbonate) so that molecules become trapped in urine that forms in the kidneys and cannot be reabsorbed from the urine back into the bloodstream prior to urinary excretion. This phenomonon is know as "ion trapping" and is the same mechanism that allows drugs to accumulate in fetal circulation in pregnant women, often to the detriment of the fetus. The underlying principle is the pka of a substance (ph at which half a substance is ionized/charged/water soluble and the other half is unionized/uncharged/lipid soluble. A small change in ph of a medium can have profound effects on the substances dissolved within that medium and the ability of those substances to cross biological membranes which are lipids. My fingers hurt so I can't type anymore. Good luck with the pee test dude.
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Old 12-06-2008, 09:46 PM
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If you have smoked for that long and that much its going to take more than a month to get clean. A friend of mine smoked for about as long as you and just about as much. He went away to Australia for two and a half months and when he came back he got tested and was still dirty. I talked to him about it and he swears he did not smoke while in Australia.
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Old 12-07-2008, 01:17 AM
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I agee with the 1 month+... Physical withdrawal will be 2 weeks max... and nothing compared to leaving cigarettes...

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