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  #11    
Old 10-31-2009, 10:24 PM
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Originally Posted by maxwelljr View Post
....technically, psilocybin is a poison....
Haha, clearly you aren't very knowledgeable in the world of neuropharmacology. Psilocybin is the phosphate ester of the psilocin molecule. Mushrooms contain more psilocybin but still trace amounts of psilocin, psilocin is more easily oxidated that psilocybin, so that accounts for the differential. When mushrooms are ingested the psilocybin is rapidly dephosphorylated into psilocin. Now when the psilocin is absorbed into your blood stream through your stomach and intestine lining, it passes through the blood-brain-barrier and binds to specific neuro receptors causing the psychoactive effects. The psilocin molecule closely resembles the several naturally occurring, in the human body, tryptamines so it can be assumed that it binds to similar receptor. So clearly as you can see that it is not actually a poison, but it can be argued that anything is technically a poison, even though oxygen is needed to live to much can cause many problems to the body in a matter of minutes. I don't want to do the googling but I could bet that alcohol is more toxic, carcinogenic, and overly harmful than most heavy psycadelics, including psilocin, LSD, MDMA, and Mescaline.

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  #12    
Old 11-01-2009, 04:01 AM
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Oh, I just figured his mate said they were death caps.. So that is why I referred to the Amanita Muscaria.
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Old 11-01-2009, 04:05 AM
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Originally Posted by Mr.KushMan View Post
Haha, clearly you aren't very knowledgeable in the world of neuropharmacology. Psilocybin is the phosphate ester of the psilocin molecule. Mushrooms contain more psilocybin but still trace amounts of psilocin, psilocin is more easily oxidated that psilocybin, so that accounts for the differential. When mushrooms are ingested the psilocybin is rapidly dephosphorylated into psilocin. Now when the psilocin is absorbed into your blood stream through your stomach and intestine lining, it passes through the blood-brain-barrier and binds to specific neuro receptors causing the psychoactive effects. The psilocin molecule closely resembles the several naturally occurring, in the human body, tryptamines so it can be assumed that it binds to similar receptor. So clearly as you can see that it is not actually a poison, but it can be argued that anything is technically a poison, even though oxygen is needed to live to much can cause many problems to the body in a matter of minutes. I don't want to do the googling but I could bet that alcohol is more toxic, carcinogenic, and overly harmful than most heavy psycadelics, including psilocin, LSD, MDMA, and Mescaline.

Peace
No arguing here, I've just seen my fair share of truffles, and I've done a bit of looking into several kinds, and yes Oxygen is very caustic, I am well aware. I wasn't arguing that it was worse than other things, I was simply stating that it's technically a poison. I feel that you were sort of rude about that?
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  #14    
Old 11-01-2009, 05:05 AM
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Anything is a poison at a high enough dose, but usually the term poison is reserved for highly toxic substances...psilocybin is less toxic than aspirin, and aspirin is not considered a poison, so I would not consider psilocybin a poison.
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Old 11-01-2009, 05:06 AM
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i would think the fucking home made beer would kill you what did that shit taste like? if you didnt get sick from the shrooms just stop worrying about it and imagine you ate a piece of food that made you sick. Instead of thinking your gonna die I would be more pissed that I spent the entire night with homemade beer and fake ass shrooms and looking at each other saying "do you feel anything? "
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Old 11-01-2009, 05:13 AM
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1 and 50 are pretty far away from each other, how did u get numbers confused?.......
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Old 11-01-2009, 06:03 AM
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Lol, you don;t trip off deathcaps, if you tripped balls, you are all good.
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Old 11-01-2009, 07:50 AM
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Psilocybin and all of those related chemicals are technically hallucinogenic toxins of the Psilocybe and Panaeolus mushrooms.
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  #19    
Old 11-01-2009, 11:09 PM
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Lol, I'd hardly concider something you need to eat your own body weight of, as toxic...
Shit, you'd be dead if you tried to drink that much water too.
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Old 11-01-2009, 11:14 PM
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Lol, I'd hardly concider something you need to eat your own body weight of, as toxic...
Shit, you'd be dead if you tried to drink that much water too.
thats why he said technically. lol
 

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