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Old 06-30-2007, 06:40 PM
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Default laughing/happy gas?
in a week im gettin a couple cavitys filled and ive had the gas b4 its a pretty good high but im curious if anyone on here knows if it has any negative health effects even in a controled medical environment
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Old 07-01-2007, 01:53 PM
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HEALTH HAZARD INFORMATION
* Routes of Exposure
Exposure to nitrous oxide occurs through inhalation. * Summary of toxicology
1. Effects on Animals: Nitrous oxide has central nervous system, teratogenic, bone marrow, and liver effects in animals [ACGIH 1991]. Rats exposed to an 80 percent concentration for 2 or more days showed signs of bone marrow toxicity [ACGIH 1991]. However, rats exposed to a 1 percent concentration of nitrous oxide for periods ranging from 7 days to 6 months showed no bone marrow effects [ACGIH 1991]. Exposure to nitrous oxide also causes neurotoxic (spinal cord lesions, demyelination, peripheral neuropathy) and hepatotoxic (focal inflammatory lesions) effects in experimental animals [ACGIH 1991]. In one study, pregnant rats were exposed to 50 percent nitrous oxide for 24 hours/day starting on day 8 of gestation and continuing for 1, 2, 4, or 6 days; dose-related embryolethal and teratogenic effects occurred among the offspring. The most common effects were embryonic death, resorption, and abnormalities of the ribs and vertebrae [Rom 1992]. Nitrous oxide was negative in three carcinogenicity assays in mice and rats exposed to concentrations as high as 400,000 ppm for 4 hours/day, 5 days/week for 78 weeks [ACGIH 1991]. The results of mutagenicity assays involving nitrous oxide were negative [ACGIH 1991].
2. Effects on Humans: Nitrous oxide is an asphyxiant at high concentrations. At lower concentrations, exposure causes central nervous system, cardiovascular, hepatic, hematopoietic, and reproductive effects in humans [Hathaway et al. 1991]. At a concentration of 50 to 67 percent (500,000 to 670,000 ppm) nitrous oxide is used to induce anesthesia in humans [Rom 1992]. Patients exposed to a 50:50 mixture of nitrous oxidexygen for prolonged periods to induce continuous sedation developed bone marrow depression and granulocytopenia [Hathaway et al. 1991; ACGIH 1991]. Although most patients recover, several deaths from aplastic anemia have been reported [Hathaway et al. 1991]. Neurotoxic effects occur after acute exposure to concentrations of 80,000 to 200,000 ppm and above; effects include slowed reaction times and performance decrements [Hathaway et al. 1991]. Long-term occupational exposure (dentists, dental assistants) has been associated with numbness, difficulty in concentrating, paresthesias, and impairment of equilibrium [Hathaway et al. 1991; ACGIH 1991]. In one study, exposure to 50 ppm nitrous oxide was associated with a decrement in audiovisual performance, but this result has not been duplicated in other studies [ACGIH 1991]. Epidemiological studies, primarily of operating room personnel, have shown increased risks of spontaneous abortion, premature delivery, and involuntary infertility among these occupationally exposed populations [ACGIH 1991; Hathaway et al. 1991].
* Signs and symptoms of exposure
1. Acute exposure: The signs and symptoms of acute exposure to nitrous oxide include dizziness, difficult breathing, headache, nausea, fatigue, and irritability. Acute exposure to nitrous oxide concentrations of 400,000 to 800,000 ppm may cause loss of consciousness [Sittig 1991].
2. Chronic exposure: The signs or symptoms of chronic overexposure to nitrous oxide may include tingling, numbness, difficulty in concentrating, interference with gait, and reproductive effects.
EMERGENCY MEDICAL PROCEDURES
* Emergency medical procedures: [NIOSH to supply]
3. Rescue: Remove an incapacitated worker from further exposure and implement appropriate emergency procedures (e.g., those listed on the Material Safety Data Sheet required by OSHA's Hazard Communication Standard [29 CFR 1910.1200]). All workers should be familiar with emergency procedures, the location and proper use of emergency equipment, and methods of protecting themselves during rescue operations.
EXPOSURE SOURCES AND CONTROL METHODS
The following operations may involve nitrous oxide and lead to worker exposures to this substance:

* The manufacture and transportation of nitrous oxide * Use as an anesthetic gas
* Use as a propellant (foaming agent) in whipped creams
* Use as a leak detecting agent on natural gas pipelines
* Use as an oxidant for the production of organic compounds
* Use in rocket fuel formulations
* Use in the manufacture of nitrates from alkali metals
Methods that are effective in controlling worker exposures to nitrous oxide, depending on the feasibility of implementation, are as follows:

* Process enclosure
* Local exhaust ventilation
* General dilution ventilation
* Personal protective equipment Workers responding to a release or potential release of a hazardous substance must be protected as required by paragraph (q) of OSHA's Hazardous Waste Operations and Emergency Response Standard [29 CFR 1910.120]. I read these all the time, this is a good one they are more fun to read blazed
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Old 07-01-2007, 02:04 PM
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Basically exposer to a compound needs to be measured in 2 ways, the amount of time exposed to the compound and the amount of the compound exposed to. You are going to receive a single dose at a medium size so your overall exposure will be moderate and should pose no to minimal risk of health effects. I add minimal just because every body is different and different people are more or less sensitive to a compound.
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Old 08-22-2007, 02:31 PM
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i vomit when im on it for more then 30min
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Old 08-23-2007, 09:42 AM
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I love laughing gass/nitrous oxide, they sell it at raves in balloons and it is a wonderful feeling.
It lifts my mood loads too!
Dont worry about it and look forward to the experience
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Old 08-28-2007, 02:25 PM
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feels like an atari game i like it
 

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