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Synonyms: Ankvin, Baktinor, Girablok, Kvinoloks, Lokson, Negafloks, Nolitsin, Norbaktin, Norilet, Normaks, Noroksin, Norfloks, renormalization, Sofazin, Spektrama, Chibroksin, Yutibid, Anquin, Baccidal, Bactinor, Barazan, Buccidal, Chibroxin, Espeden, Floxacin, Fulgram, Girabloc, Lexinor, Loxon, Negaflox, Nolicin, Nolion, Norbactin, Norfaxin, Norilet, Normax, Norocin, Noroxin, Primoxin, Renor, Sofazin, Spectrama, Uroctal, Utibid, Zoroxin etc.


Different chemical structure from pefloksatsina absence of a methyl group at piperazinilnom nucleus.


Active against most gram-negative and some Gram-positive (Staphylococcus) bacteria. No effect on anaerobes.


Absorbed quickly, but not all (20-40% dose), C max is 60-90 min, T - 2,5-4,5 h, well into the organs and tissues, being a minor biotransformation in the liver and excreted in urine mainly unchanged.


Apply for urinary tract infections, intestinal infections (shigellosis, salmonellosis), eye infections, and otitis, prostatitis and gonorrhea.


Assign inside and topically.


Inside (1 hour before or 2 hours after meals) are usually used to 0,2-0,4 g 2-3 times daily for 7-10 days (for recurrent urinary tract infections - up to 12 weeks) with acute gonococcal urethritis, pharyngitis, proctitis, cervicitis - 0.8 g once.


Locally appoint 1-2 drops of the affected eye every 2 hours or 4 times a day and 4 drops in each ear 3-4 times a day.


Can cause side effects from the gastrointestinal tract (dyspepsia), urinary tract infection (dysuria), central nervous system (insomnia, hallucinations), cardiovascular system (tachycardia, arrhythmia, hypotension), as well as dysbiosis, candidiasis, leukopenia, allergic skin reactions.


The drug is contraindicated in severe renal failure, pregnancy, lactation and the age of 15 years.


Method of production: tablets of 0.2, 0.4 and 0.8 g (N. 10, 20); 0,3% solution (eye and ear drops) in bottles, droppers to 5 ml (Normaks).