Quote:
Originally Posted by just for the magic
personally, i know less than fuck all on most matters relating to gardening. So...is it just a myth that has been perpetuated by uneducated(on the subject) folk? I remember a friend of mine not cloning after 4-5 crops because he stubbornly held the belief that degradation was inevitable. I remember the nobber waiting a year for more clones to come. In his defence, great info sites like this were not around back then........ I am fucking old 
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You might lose some vigor by using the same mother plant for too long, but when you take a healthy clone it's like resetting a stopwatch to zero. You are starting from scratch with that particular genetic sequence. Every time.
With the new advances in tissue cultures, all you need now is a few milligrams of living plant matter to grow a full plant that is an identical genetic copy.
If a clone, or line of clones goes bad, it's a 99.9% chance that it's due to environmental conditions, and not from some sort of genetic drift.