I have found that anything longer than a year should be restarted. You can actually start a new mother off of the same plant, but the vigor will wane.Start a newmother from seed and the renewed vigor is astounding: higher yield, faster & resists those pesky spider mites the same way I resist coke whores.
These bits of wisdom comes not only from myself, but also my professor - I was a horticulture major & that is how many plants are propagated; take cuttings, put them in the spray-mister & you have a new plant. Anybody that owns a greenhouse will tell you what I just did.
The mother will be ready again for clones in 2 weeks to 3, to??? You will look & tell...we took clones every week, so we had a payday every week, there were 15 to 20 mothers & we just looked for the one that was ready that week.
You can take hundreds of clones off one mother...just like a human, look at a woman that has had 10 kids...they wear out!