Every once in a while I take a hit, mind you, a hit of salvia, out of a one hitter, I use 10x and I get a different feeling each time, but so far never bad, when dealing with this kind of substance you have to be in the right mind set, and dont take 3 bong hits cause thats is way too much. If it does not kick in, wait about an hour or so and take another, it will kick in, and you wont be losing it by taking too much at once. would you take 3 hits of acid if you did not know how strong it was? hmm. this is a very strange substance and should not be taken without forethought, be sure you are not alone (but not in a crowd either) one other person is preferred to watch over you. It has great miind opening powers and does not leave you with a hangover feeling afterwards, rather I feel refreshed after it, but not like I want to take another hit to get back there. I dont even fill the one hitter all the way, as a fully packed one is still too much. Anyway this is not for everyone, used to trip acid a lot some 20 years ago, this gets me a similar feeling without loosing a whole weekend and brain tissue to get there. Please do not abuse this substance, it is way too powerful to play with. Just my thoughts.