The seven last plagues in Revelation are:
First plague: The contents of the first bowl will cause painful sores upon those “who had the mark of the beast and those who worshiped his image” (Revelation 16:2). It appears these painful, open sores will be caused by some sort of skin disease or infection.
Second plague: When this bowl is poured out, the sea will become blood and cause all life in it to die (verse 3). The death of saltwater marine life will destroy a major food source for millions of people.
Third plague: After the third angel pours out its bowl, the rivers and springs of water will become blood (verse 4). This plague will destroy freshwater fish—even further impacting the food supply for millions of people.
Fourth plague: The fourth bowl will cause the sun to become so hot as “to scorch men with fire” (verse
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Fifth plague: This punishment will bring darkness, pains and sores (verses 10-11).
Sixth plague: The bowl containing this plague will be poured out on the Euphrates River, causing it to dry up and make land travel easier for the armies of “the kings of the earth and of the whole world” to assemble at
Armageddon (the area of Megiddo, which is approximately 18 miles or 30 kilometers southeast of the modern city of Haifa). From this location, the assembled armies will then advance toward Jerusalem for a final battle against Jesus Christ (verses 12-16).
Seventh plague: This final plague will consist of “noises and thunderings and lightnings” and “such a mighty and great earthquake as had not occurred since men were on the earth” (verse 1
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Babylon, a powerful false religion, will fall (verse 19, compare Revelation 18:2) and there will be devastating hail, with hailstones weighing up to a “talent”—approximately 100 pounds (verse 21).